Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

535 questions · 545 findings · 129 reviews · Headline outcomes only

No studies found 131 · 24%GRADE not reported 30 · 5.5%Very low 123 · 22.6%Low 136 · 25%Moderate 98 · 18%High 27 · 5%

Hysterectomy (simple or radical) with radiotherapy vs Radiotherapy alone

Progression‐free survival (PSF) · women with locally advanced cervical cancer

Hysterectomy (simple or radical) with radiotherapy showed no clear difference in progression‐free survival Median compared with radiotherapy alone (low certainty).

1 finding from 1 review

Hysterectomy (simple or radical) with radiotherapy vs Radiotherapy alone

Death (all causes) · women with locally advanced cervical cancer

Hysterectomy (simple or radical) with radiotherapy showed no clear difference in overall survival Median compared with radiotherapy alone (low certainty).

1 finding from 1 review

Hysterectomy (radical) with neoadjuvant chemotherapy vs chemoradiotherapy alone

Death (all causes) · women with locally advanced cervical cancer

Hysterectomy (radical) with neoadjuvant chemotherapy showed no clear difference in overall survival Median compared with chemoradiotherapy alone (moderate certainty).

1 finding from 1 review