Question · asked by 1 review

Hysterectomy (radical) with neoadjuvant chemotherapy vs chemoradiotherapy alone: Death (all causes)

Hysterectomy (radical) with neoadjuvant chemotherapy showed no clear difference in overall survival Median compared with chemoradiotherapy alone (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Hysterectomy (radical) with neoadjuvant chemotherapy vs chemoradiotherapy alone
Overall survival Median · women with locally advanced cervical cancer
Hysterectomy (radical) with neoadjuvant chemotherapy showed no clear difference in overall survival Median compared with chemoradiotherapy alone (moderate certainty).
Hysterectomy with radiotherapy or chemotherapy or both for women with locally advanced cervical cancer (2022) · Cochrane Headline outcomes only
HR 0.94 [0.76, 1.16]2 studies · 1253 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Hysterectomy with radiotherapy or chemotherapy or both for women with locally advanced cervical cancer
2022 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.