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Evidence found and GRADE certainty

3,696 questions · 3,815 findings · 855 reviews

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No studies found 573 · 15%GRADE not reported 374 · 9.8%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Postoperative systemic antibiotics (phenoxymethylpenicillin/penicillin VK, 7-day course), partial or total chemo-mechanical debridement and analgesics vs Matched placebo, partial or total chemo-mechanical debridement and analgesics

Percussion pain at 7 days · Adults with a symptomatic necrotic tooth or localised acute apical abscess (no signs of spreading infection or systemic involvement)

Postoperative systemic antibiotics… showed no clear difference in percussion pain at 7 days compared with matched placebo, partial or total chemo-mechanical debridement and…; GRADE not reported.

1 finding from 1 review

Postoperative systemic antibiotics (phenoxymethylpenicillin/penicillin VK, 7-day course), partial or total chemo-mechanical debridement and analgesics vs Matched placebo, partial or total chemo-mechanical debridement and analgesics

Pain at 7 days · Adults with a symptomatic necrotic tooth or localised acute apical abscess (no signs of spreading infection or systemic involvement)

It is very uncertain whether postoperative systemic antibiotics… changes pain at 7 days compared with matched placebo, partial or total chemo-mechanical debridement and… (very low certainty).

1 finding from 1 review

Inositol supplementation IV initially followed by enteral administration (repeat doses of 80 mg/kg/day) in preterm infants born at less than 30 weeks' PMA vs placebo

BPD or death by it prior to 37 weeks' PMA (outcomes collected through first event: death, hospital discharge, hospital transfer, or 120 days after birth) · preterm infants with or at risk of respiratory distress syndrome

Inositol supplementation IV initially followed by enteral… showed no clear difference in BPD or death by it prior to 37 weeks' PMA (outcomes collected… compared with placebo (high certainty).

1 finding from 1 review

Inositol supplementation IV initially followed by enteral administration (repeat doses of 80 mg/kg/day) in preterm infants born at less than 30 weeks' PMA vs placebo

All‐cause mortality (outcome collected through first event: death, hospital discharge, hospital transfer, or 120 days after birth) · preterm infants with or at risk of respiratory distress syndrome

Inositol supplementation IV initially followed by enteral… showed no clear difference in all‐cause mortality (outcome collected through first event: death,… compared with placebo (moderate certainty).

1 finding from 1 review

TENS vs sham TENS

Resolution of daytime urinary incontinence · children aged 3 to 18 years with daytime urinary incontinence

Transcutaneous electrical nerve stimulation (TENS) may leads to higher resolution of daytime urinary incontinence after 7 to 20 weeks'… compared with placebo (sham TENS) (low certainty).

1 finding from 1 review

Voiding education with uroflow feedback and urotherapy vs urotherapy alone

Resolution of daytime urinary incontinence · children aged 5 to 16 years with daytime urinary incontinence

Voiding education with uroflow feedback and urotherapy showed no clear difference in resolution of daytime urinary incontinence at 6 to 12 months after 6… compared with urotherapy alone (low certainty).

1 finding from 1 review

Timer watch plus standard urotherapy vs urotherapy alone

Resolution of daytime urinary incontinence · children aged 5 to 14 years with overactive bladder and at least one episode of daytime urinary incontinence per week

It is very uncertain whether timer watch plus standard urotherapy changes resolution of daytime urinary incontinence after 3 months of treatment compared with standard urotherapy alone (very low certainty).

1 finding from 1 review

Transcutaneous electrical nerve stimulation (TENS) and standard urotherapy vs pelvic floor muscle training (PFMT) with electromyographic biofeedback and standard urotherapy

Resolution of daytime urinary incontinence · children aged 5 to 16 years with daytime urinary incontinence

It is very uncertain whether transcutaneous electrical nerve stimulation (TENS) and standard… changes resolution of daytime urinary incontinence compared with pelvic floor muscle training (PFMT) with electromyographic… (very low certainty).

1 finding from 1 review

Pelvic floor muscle training (PFMT) with electromyography biofeedback and standard urotherapy vs pelvic floor muscle training without biofeedback but with standard urotherapy

Resolution of daytime urinary incontinence · children aged 5 to 15 years with dysfunctional elimination syndrome, 41/59 with daytime urinary incontinence

It is very uncertain whether pelvic floor muscle training (PFMT) with electromyography… changes resolution of daytime urinary incontinence at 12 months (9 months… compared with pelvic floor muscle training without biofeedback but with standard… (very low certainty).

1 finding from 1 review

Pelvic floor muscle training vs anticholinergics

Resolution of daytime urinary incontinence · children aged 5‐14 years with daytime urinary incontinence or post‐micturition dribbling

It is very uncertain whether pelvic floor muscle training changes resolution of daytime urinary incontinence at end of treatment or 1… compared with anticholinergics (very low certainty).

1 finding from 1 review

TENS vs anticholinergics

Resolution of daytime urinary incontinence · children aged 4 to 17 years with daytime urinary incontinence

It is very uncertain whether transcutaneous electrical nerve stimulation (TENS) changes resolution of daytime urinary incontinence at 3 months compared with anticholinergics (very low certainty).

1 finding from 1 review

Pelvic floor muscle training (PFMT) with urotherapy vs urotherapy alone

Resolution of daytime urinary incontinence · children aged 3 to 17 years with daytime urinary incontinence

It is very uncertain whether pelvic floor muscle training (PFMT) with urotherapy changes resolution of daytime urinary incontinence after 12 months of… compared with urotherapy alone (very low certainty).

1 finding from 1 review