Findings

What do systematic reviews say?

123 questions · 124 findings · 10 reviews · Kidney and Transplant

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No studies found 45 · 36.3%GRADE not reported 0 · 0%Very low 20 · 16.1%Low 47 · 37.9%Moderate 10 · 8.1%High 2 · 1.6%

Intervention not reported

Epoetin · CKD patients (any stage) treated for anaemia

1 finding from 1 review

Continuous erythropoiesis receptor activator (CERA) for the anaemia of chronic kidney disease 2017 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1846 participants
Low

Intervention not reported

Darbepoetin · CKD patients (any stage) treated for anaemia

1 finding from 1 review

Continuous erythropoiesis receptor activator (CERA) for the anaemia of chronic kidney disease 2017 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1657 participants
Low

Intervention not reported

CERA Q4W · CKD patients (any stage) treated for anaemia

1 finding from 1 review

Continuous erythropoiesis receptor activator (CERA) for the anaemia of chronic kidney disease 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 822 participants
Low

Intervention not reported

CERA higher dose · CKD patients (any stage) treated for anaemia

1 finding from 1 review

Continuous erythropoiesis receptor activator (CERA) for the anaemia of chronic kidney disease 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 42 participants
Low

Intervention not reported

Hypertension · CKD patients (any stage) treated for anaemia

The review found no eligible studies for this question.

1 finding from 1 review

Continuous erythropoiesis receptor activator (CERA) for the anaemia of chronic kidney disease 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

PLACEBO · CKD patients (any stage) treated for anaemia

1 finding from 1 review

Continuous erythropoiesis receptor activator (CERA) for the anaemia of chronic kidney disease 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 235 participants
Low

Intervention not reported

Mortality · patients with acute kidney injury

The intervention showed no clear difference in mortality (moderate certainty).

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
RR 0.76 [0.5, 1.15]
3 studies · 163 participants
Moderate

Intervention not reported

Serum bicarbonate (mmol/L) · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 163 participants
Low

Intervention not reported

Serum creatinine (µmol/L) · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 137 participants
Low

Intervention not reported

Serum lactate (mmol/L) · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 171 participants
Moderate

Intervention not reported

Serum base excess · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 145 participants
Low

Intervention not reported

Serum pH · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 171 participants
Low

Intervention not reported

pCO2 · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 151 participants
Low

Intervention not reported

Hypotensive events · patients with acute kidney injury

The intervention probably leads to lower hypotensive events (moderate certainty).

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
RR 0.44 [0.26, 0.75]
1 study · 20 participants
Moderate

Intervention not reported

Cardiovascular complications · patients with acute kidney injury

The intervention probably leads to lower cardiovascular complications (moderate certainty).

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
RR 0.39
1 study · 20 participants
Moderate

Intervention not reported

All‐cause mortality · patients with rhabdomyolysis

The intervention showed no clear difference in all‐cause mortality (low certainty).

1 finding from 1 review

Continuous renal replacement therapy (CRRT) for rhabdomyolysis 2014 · Cochrane Headline outcomes only
RR 0.17 [0.02, 1.37]
1 study · 43 participants
Low

Intervention not reported

Length of hospital stay · patients with rhabdomyolysis

1 finding from 1 review

Continuous renal replacement therapy (CRRT) for rhabdomyolysis 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Low

Intervention not reported

Serum myoglobin: day 4 · patients with rhabdomyolysis

1 finding from 1 review

Continuous renal replacement therapy (CRRT) for rhabdomyolysis 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
Low

Intervention not reported

Serum myoglobin: day 8 · patients with rhabdomyolysis

1 finding from 1 review

Continuous renal replacement therapy (CRRT) for rhabdomyolysis 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
Low

Intervention not reported

Serum myoglobin: day 10 · patients with rhabdomyolysis

1 finding from 1 review

Continuous renal replacement therapy (CRRT) for rhabdomyolysis 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
Low