Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

159 questions · 168 findings · 21 reviews

No studies found 40 · 23.8%GRADE not reported 15 · 8.9%Very low 45 · 26.8%Low 33 · 19.6%Moderate 30 · 17.9%High 5 · 3%

Interventions (ibuprofen, tolfenamic acid, aspirin, tranexamic acid) vs placebo or active comparators (paracetamol, tranexamic acid)

Menstrual blood loss % occurrence of heavy menstrual bleeding (alkaline hematin method)

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Stroke (fatal and non‐fatal) (a. ticlopidine vs aspirin) (b. clopidogrel vs aspirin & dipyramidole) · patients with type 2 diabetes mellitus

The intervention probably leads to lower stroke (fatal and non‐fatal) (a. ticlopidine vs aspirin) (b.… (moderate certainty).

1 finding from 1 review

Cilostazol vs aspirin

MACE · adults within 180 days of non‐cardioembolic ischaemic stroke or transient ischaemic attack and a clinical history of prior intracerebral…

Summary of findings table ‐ Cilostazol showed no clear difference in MACE compared with aspirin (low certainty).

1 finding from 1 review

Cilostazol vs aspirin

Death · adults within 180 days of non‐cardioembolic ischaemic stroke or transient ischaemic attack and a clinical history of prior intracerebral…

Summary of findings table ‐ Cilostazol showed no clear difference in death compared with aspirin (low certainty).

1 finding from 1 review

Cilostazol vs aspirin

Intracerebral haemorrhage (ICH) · adults within 180 days of non‐cardioembolic ischaemic stroke or transient ischaemic attack and a clinical history of prior intracerebral…

Summary of findings table ‐ Cilostazol showed no clear difference in intracerebral haemorrhage (ICH) compared with aspirin (low certainty).

1 finding from 1 review

Human placental extract vs Disprin (aspirin/betamethasone)

Improvement in mucositis · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis

Human placental extract led to higher improvement in mucositis compared with disprin (aspirin/betamethasone); GRADE not reported.

1 finding from 1 review