Change in gingival recession (REC) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
Enamel matrix derivative (EMD; Emdogain) showed no clear difference in change in gingival recession (REC) compared with placebo or control (same surgical or non-surgical intervention… (low certainty).
1 finding from 1 review
Marginal bone level change · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review
Change in probing attachment level (PAL) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review
Change in probing pocket depth (PPD) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
Enamel matrix derivative (EMD; Emdogain) showed no clear difference in change in probing pocket depth (PPD) compared with guided tissue regeneration (GTR) with barriers (low certainty).
1 finding from 1 review
Change in gingival recession (REC) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
Enamel matrix derivative (EMD; Emdogain) may leads to higher change in gingival recession (REC) compared with guided tissue regeneration (GTR) with barriers (low certainty).
1 finding from 1 review
Change in probing pocket depth (PPD) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
Enamel matrix derivative (EMD; Emdogain) may leads to higher change in probing pocket depth (PPD) compared with placebo or control (same surgical or non-surgical intervention… (low certainty).
1 finding from 1 review
Change in probing attachment level (PAL) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
Enamel matrix derivative (EMD; Emdogain) may leads to higher change in probing attachment level (PAL) compared with placebo or control (same surgical or non-surgical intervention… (low certainty).
1 finding from 1 review
Tooth loss · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review
Postoperative complications (infection) / adverse events · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
Enamel matrix derivative (EMD; Emdogain) led to lower postoperative complications (infection) / adverse events compared with guided tissue regeneration (GTR) with barriers; GRADE not reported.
1 finding from 1 review
RR 0.12 [0.02, 0.85]
3 studies
GRADE not reported
Tooth loss · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review
Postoperative complications (infection) / adverse events · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review
Change in probing attachment level (PAL) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
Enamel matrix derivative (EMD; Emdogain) showed no clear difference in change in probing attachment level (PAL) compared with guided tissue regeneration (GTR) with barriers (low certainty).
1 finding from 1 review
Change in gingival recession (REC) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
Enamel matrix derivative (EMD; Emdogain) led to lower change in gingival recession (REC) compared with various bone grafting (BG) procedures (animal-derived or synthetic…; GRADE not reported.
1 finding from 1 review
MD -1.60 [-2.74, -0.46]
1 study
GRADE not reported
Marginal bone level change · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
The review found no eligible studies for this question.
1 finding from 1 review
Aesthetics · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
The review found no eligible studies for this question.
1 finding from 1 review
Change in probing pocket depth (PPD) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review
Tooth loss · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review
Marginal bone level change · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review
Postoperative complications (infection) / adverse events · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review
No particular adverse events or infection attributable to EMD in any trial; no differences in pain, edema, hematoma, wound dehiscence or root sensitivity (Tonetti 2002).
9 studies
GRADE not reported
PAL gain < 2 mm (dichotomous) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
Enamel matrix derivative (EMD; Emdogain) led to lower PAL gain < 2 mm (dichotomous) compared with placebo or control (same surgical or non-surgical intervention…; GRADE not reported.
1 finding from 1 review
RR 0.53 [0.34, 0.82]
6 studies
GRADE not reported