Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,696 questions · 3,815 findings · 855 reviews

No studies found 573 · 15%GRADE not reported 374 · 9.8%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Very potent vs potent topical corticosteroid

Local adverse events: skin thinning; end of treatment (1 to 3 weeks) · adults with eczema

It is very uncertain whether very potent changes local adverse events: skin thinning; end of treatment (day 11‐day 22) compared with potent topical corticosteroid (very low certainty).

1 finding from 1 review

Moderate‐potency vs mild‐potency topical corticosteroid

Systemic adverse events: abnormal cortisol; end of treatment (1‐6 weeks) · children and adults with mild to severe eczema

It is very uncertain whether moderate‐potency changes systemic adverse events: abnormal cortisol; end of treatment (6‐28… compared with mild‐potency topical corticosteroid (very low certainty).

1 finding from 1 review

Running shoes recommended and selected on foot posture vs running shoes not recommended and selected on foot posture

Injury Incidence Rate (injuries / 1000 person‐days)a · military personnel

Running shoes recommended and selected on foot posture showed no clear difference in injury Incidence Rate (injuries / 1000 person‐days)a compared with running shoes not recommended and selected on foot posture (moderate certainty).

1 finding from 1 review

Negative pressure wound therapy vs conventional open wound healing

Time to complete healing · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

It is very uncertain whether topical negative pressure wound therapy changes time to wound healing (days) compared with conventional open wound healing (very low certainty).

1 finding from 1 review

Lietofix cream vs iodoform dressing

Proportion of wounds healed · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

Lietofix cream may leads to higher proportion of wounds healed at 30 days compared with iodoform dressing (low certainty).

1 finding from 1 review

Negative pressure wound therapy vs conventional open wound healing

Proportion of wounds healed · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

It is very uncertain whether topical negative pressure wound therapy changes proportion of wounds healed at 30 days compared with conventional open wound healing (very low certainty).

1 finding from 1 review

Hydrogel dressings vs povidone‐iodine

Time to complete healing · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

It is very uncertain whether hydrogel dressing changes time to wound healing (days) compared with wound cleaning with 10% povidone iodine (very low certainty).

1 finding from 1 review

Platelet‐rich plasma gel vs absorbent sterile cotton gauze

Time to complete healing · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

Platelet‐rich plasma gel may leads to higher time to wound healing (days) compared with absorbent sterile cotton gauze (low certainty).

1 finding from 1 review

Gentamicin‐impregnated collagen sponge vs no dressing

Time to complete healing · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

It is very uncertain whether gentamicin‐impregnated collagen sponge changes time to wound healing (days) compared with no dressing (very low certainty).

1 finding from 1 review

Dialkylcarbamoyl chloride (DACC)‐coated dressing vs alginate dressing

Proportion of wounds healed · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

It is very uncertain whether dialkylcarbamoyl chloride (DACC)‐coated dressing changes proportion of wounds healed at 25 days compared with alginate dressing (very low certainty).

1 finding from 1 review