Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,539 questions · 2,602 findings · 424 reviews · Headline outcomes only

No studies found 572 · 22%GRADE not reported 189 · 7.3%Very low 527 · 20.3%Low 685 · 26.3%Moderate 514 · 19.8%High 115 · 4.4%

Intervention not reported

Long‐term death or disability ( · patients with acute ischaemic stroke

The intervention may leads to lower long‐term death or disability ( (low certainty).

1 finding from 1 review

Supervised exercise therapy vs home exercises

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with patellofemoral pain syndrome (symptoms > 2 months (1 study); not stated (1 study))

It is very uncertain whether supervised exercises changes usual pain (long‐term) VAS (0 to 10; higher scores mean worse pain) compared with home exercises (very low certainty).

1 finding from 1 review

Supervised exercise therapy vs home exercises

Functional ability · patients with patellofemoral pain syndrome (symptoms > 2 months (1 study); not stated (1 study))

It is very uncertain whether supervised exercises changes functional ability (long‐term) FIQ (number of patients in top (best… compared with home exercises (very low certainty).

1 finding from 1 review

Closed kinetic chain exercises vs open kinetic chain exercises

Pain during activity (long‐term) VAS (0 to 10; higher scores mean worse pain) · patients with patellofemoral pain syndrome (symptoms > 4 weeks (1 study); symptoms > 6 weeks (1 study); symptoms > 8 weeks (1 study); not…

It is very uncertain whether closed kinetic chain exercises changes pain during activity (long‐term) VAS (0 to 10; higher scores mean… compared with open kinetic chain exercises (very low certainty).

1 finding from 1 review

Closed kinetic chain exercises vs open kinetic chain exercises

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with patellofemoral pain syndrome (symptoms > 4 weeks (1 study); symptoms > 6 weeks (1 study); symptoms > 8 weeks (1 study); not…

It is very uncertain whether closed kinetic chain exercises changes usual pain (long‐term) VAS (0 to 10; higher scores mean worse pain) compared with open kinetic chain exercises (very low certainty).

1 finding from 1 review

Closed kinetic chain exercises vs open kinetic chain exercises

Functional ability · patients with patellofemoral pain syndrome (symptoms > 4 weeks (1 study); symptoms > 6 weeks (1 study); symptoms > 8 weeks (1 study); not…

It is very uncertain whether closed kinetic chain exercises changes functional ability (long‐term) AKPS (0 to 100; higher scores mean… compared with open kinetic chain exercises (very low certainty).

1 finding from 1 review

Target of exercise: hip + knee vs knee exercises

Pain during activity (long‐term) VAS (0 to 10; higher scores mean worse pain) · patients with patellofemoral pain syndrome (symptoms > 1 month (3 studies); symptoms > 2 months (1 study); symptoms > 3 months (2…

It is very uncertain whether target of exercise: hip + knee changes pain during activity (long‐term) NPRS (0 to 10; higher scores mean… compared with knee exercises (very low certainty).

1 finding from 1 review

Target of exercise: hip + knee vs knee exercises

Functional ability · patients with patellofemoral pain syndrome (symptoms > 1 month (3 studies); symptoms > 2 months (1 study); symptoms > 3 months (2…

It is very uncertain whether target of exercise: hip + knee changes functional ability (long‐term) Scale (0 to 100; higher scores mean… compared with knee exercises (very low certainty).

1 finding from 1 review

Target of exercise: hip + knee vs knee exercises

Recovery long‐term Number of patients at least moderately better · patients with patellofemoral pain syndrome (symptoms > 1 month (3 studies); symptoms > 2 months (1 study); symptoms > 3 months (2…

It is very uncertain whether target of exercise: hip + knee changes recovery long‐term Number of patients at least moderately better compared with knee exercises (very low certainty).

1 finding from 1 review

Exercise therapy vs a control strategy (no treatment, placebo or waiting list controls)

Pain during activity (long‐term) VAS (0 to 10; higher scores mean worse pain) · patients with patellofemoral pain syndrome (symptoms > 3 weeks (1 study); symptoms > 1 month (3 studies); symptoms > 2 months (2 studies);…

It is very uncertain whether exercise therapy changes pain during activity (long‐term) Scale (0 to 10; higher scores mean… compared with a control strategy (no treatment, placebo or waiting list controls) (very low certainty).

1 finding from 1 review