Findings

What do systematic reviews say?

4,749 questions · 17,858 findings · 1,266 reviews

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No studies found 4,359 · 24.4%GRADE not reported 2,348 · 13.1%Very low 4,634 · 25.9%Low 4,000 · 22.4%Moderate 2,052 · 11.5%High 465 · 2.6%

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Complex information, support and training interventions vs inactive control (usual care care, attention control, waitlist)

Use of health and social resources · Informal caregivers of people with dementia

Complex information, support and training interventions showed no clear difference in use of health and social resources compared with usual treatment, waiting list or attention control informations (moderate certainty).

1 finding from 1 review

Remotely delivered information, training and support for informal caregivers of people with dementia 2021 · Cochrane Headline outcomes only
Rate ratio 1.05 [0.93, 1.19]
1 study · 4776 participants
Moderate

Complex information, support and training interventions vs inactive control (usual care care, attention control, waitlist)

Institutional care ‐ nursing home placement · Informal caregivers of people with dementia

It is very uncertain whether complex information, support and training interventions changes institutional care ‐ nursing home placement compared with usual treatment, waiting list or attention control informations (very low certainty).

1 finding from 1 review

Remotely delivered information, training and support for informal caregivers of people with dementia 2021 · Cochrane Headline outcomes only
RR 0.59 [0.11, 3.11]
1 study · 34 participants
Very low

Complex information, support and training interventions vs information only

Caregiver burden · Informal caregivers of people with dementia

1 finding from 1 review

Remotely delivered information, training and support for informal caregivers of people with dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 650 participants
Low

Complex information, support and training interventions vs information only

Caregiver mood · Informal caregivers of people with dementia

1 finding from 1 review

Remotely delivered information, training and support for informal caregivers of people with dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 1100 participants
Moderate

Complex information, support and training interventions vs information only

Caregiver health‐related quality of life (HRQoL) · Informal caregivers of people with dementia

1 finding from 1 review

Remotely delivered information, training and support for informal caregivers of people with dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 257 participants
Low

Enhanced educational intervention and structured follow‐up vs standard education

Time to occurrence of new ulcer · s

The review found no eligible studies for this question.

1 finding from 1 review

Patient and lay carer education for preventing pressure ulceration in at‐risk populations 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Enhanced educational intervention and structured follow‐up vs standard education

Proportion of participants developing a new ulcer · s

The review found no eligible studies for this question.

1 finding from 1 review

Patient and lay carer education for preventing pressure ulceration in at‐risk populations 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Discontinuation with high‐intensity psychological interventions vs continuation

Successful discontinuation rate · participants with long‐term antidepressants for depressive disorders

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 690 participants
Very low

Discontinuation with high‐intensity psychological interventions vs continuation

Risk of relapse (as defined by study authors) (HR) · participants with long‐term antidepressants for depressive disorders

Discontinuation with high‐intensity psychological interventions showed no clear difference in risk of relapse (as defined by study authors) (HR) compared with continuation (low certainty).

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
HR 0.89 [0.66, 1.19]
3 studies · 690 participants
Low

Discontinuation with high‐intensity psychological interventions vs continuation

Withdrawal symptoms · participants with long‐term antidepressants for depressive disorders

The review found no eligible studies for this question.

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Discontinuation with high‐intensity psychological interventions vs continuation

Adverse events · participants with long‐term antidepressants for depressive disorders

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 690 participants
Very low

Discontinuation with high‐intensity psychological interventions vs continuation

Depressive symptoms · participants with long‐term antidepressants for depressive disorders

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 484 participants
Low

Discontinuation with high‐intensity psychological interventions vs continuation

Anxiety · participants with long‐term antidepressants for depressive disorders

The review found no eligible studies for this question.

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Discontinuation with high‐intensity psychological interventions vs continuation

Quality of life · participants with long‐term antidepressants for depressive disorders

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 455 participants
Very low

Discontinuation with high‐intensity psychological interventions vs continuation

Social and occupational functioning · participants with long‐term antidepressants for depressive disorders

The review found no eligible studies for this question.

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Discontinuation of long‐term antidepressant with minimal intervention vs usual care

Successful discontinuation rate · participants with long‐term antidepressants for depressive or anxiety disorders

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 146 participants
Low

Discontinuation of long‐term antidepressant with minimal intervention vs usual care

Relapse · participants with long‐term antidepressants for depressive or anxiety disorders

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 146 participants
Low

Discontinuation of long‐term antidepressant with minimal intervention vs usual care

Withdrawal symptoms · participants with long‐term antidepressants for depressive or anxiety disorders

The review found no eligible studies for this question.

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Discontinuation of long‐term antidepressant with minimal intervention vs usual care

Adverse events · participants with long‐term antidepressants for depressive or anxiety disorders

The review found no eligible studies for this question.

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Discontinuation of long‐term antidepressant with minimal intervention vs usual care

Depressive symptoms · participants with long‐term antidepressants for depressive or anxiety disorders

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 106 participants
Low