Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,615 questions · 1,673 findings · 190 reviews · Headline outcomes only

No studies found 278 · 16.6%GRADE not reported 85 · 5.1%Very low 328 · 19.6%Low 460 · 27.5%Moderate 402 · 24%High 120 · 7.2%

Group antenatal care vs individual antenatal care (adjusted data)

Neonatal admission to NICU · pregnant women accessing prenatal care

Group antenatal care showed no clear difference in neonatal intensive care unit (NICU) admission (admission of baby to… compared with individual antenatal care (adjusted data) (moderate certainty).

1 finding from 1 review

Group antenatal care vs individual antenatal care (adjusted data)

Satisfaction with antenatal care (possible values 81‐405, Littlefield 1987) · pregnant women accessing prenatal care

Group antenatal care probably leads to higher satisfaction with antenatal care (possible values 81‐405,… compared with individual antenatal care (adjusted data) (moderate certainty).

1 finding from 1 review

Intervention not reported

LDL‐cholesterol atorvastatin 10 mg/d · individuals with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

LDL‐cholesterol atorvastatin 20 mg/d · individuals with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

LDL‐cholesterol atorvastatin 40 mg/d · individuals with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

LDL‐cholesterol atorvastatin 80 mg/d · individuals with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

WDAEb all doses · individuals with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

Number of exacerbations of bronchiectasis Frequency of acute exacerbations of bronchiectasis · individuals with stable bronchiectasis

The intervention showed no clear difference in number of exacerbations of bronchiectasis Frequency of acute… (low certainty).

1 finding from 1 review

Intervention not reported

Hospitalisations · individuals with stable bronchiectasis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Health‐related quality of life (disease‐specific) Scale from 0 to 100; lower score indicates better HRQoL. SGRQ total score consists of weighted scores from 3 domains · individuals with stable bronchiectasis
1 finding from 1 review

Intervention not reported

Health‐related quality of life (cough‐specific) Leicester Cough Questionnaire Scale from 0 to 133; higher score indicates better HRQoL. Contains 19 questions from 3 domains on a Likert scale · individuals with stable bronchiectasis
1 finding from 1 review

Intervention not reported

Health‐related quality of life (health status) COPD Assessment Tool. Scale from 0 to 5; higher score indicates worse HRQoL Contains 10 questions with 5‐point Likert scale · individuals with stable bronchiectasis

The intervention showed no clear difference in health‐related quality of life (health status) COPD Assessment Tool.… (low certainty).

1 finding from 1 review

Intervention not reported

Respiratory symptoms (symptoms) Breathlessness, Cough and Sputum Scale Scale from 0 to 12. Lower score indicates fewer symptoms · individuals with stable bronchiectasis

The intervention showed no clear difference in respiratory symptoms (symptoms) Breathlessness, Cough and Sputum… (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events (AEs) · individuals with stable bronchiectasis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Patient‐reported functional outcomes (pooled data) · individuals more than 18 years old with distal tibial metaphyseal fractures

It is very uncertain whether the intervention changes patient‐reported functional outcomes (pooled data) (very low certainty).

1 finding from 1 review

Intervention not reported

Need for a secondary/revision operation or substantive physiotherapy for adverse outcomes (e.g. non‐union, malunion or infection) · individuals more than 18 years old with distal tibial metaphyseal fractures

It is very uncertain whether the intervention changes need for a secondary/revision operation or substantive physiotherapy… (very low certainty).

1 finding from 1 review

Intervention not reported

Symptomatic non‐union or malunion, including limping 1 year · individuals more than 18 years old with distal tibial metaphyseal fractures

It is very uncertain whether the intervention changes symptomatic non‐union or malunion, including limping 1 year (very low certainty).

1 finding from 1 review