Findings

What do systematic reviews say?

1,155 questions · 1,191 findings · 195 reviews · Headline outcomes only

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No studies found 209 · 17.5%GRADE not reported 51 · 4.3%Very low 256 · 21.5%Low 273 · 22.9%Moderate 284 · 23.8%High 118 · 9.9%

Intervention not reported

Sustained pain‐free at 24 h · adults with migraine headache ‐ moderate or severe pain

The review found no eligible studies for this question.

1 finding from 1 review

Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Sustained headache relief at 24 h · adults with migraine headache ‐ moderate or severe pain

The review found no eligible studies for this question.

1 finding from 1 review

Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Serious AE · adults with migraine headache ‐ moderate or severe pain

The review found no eligible studies for this question.

1 finding from 1 review

Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Pain‐free at 2 h · migraine headache ‐ moderate or severe pain

1 finding from 1 review

Aspirin with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 2027 participants
Moderate

Intervention not reported

Headache relief at 2 h · migraine headache ‐ moderate or severe pain

1 finding from 1 review

Aspirin with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 2027 participants
Moderate

Intervention not reported

Sustained pain‐free at 24 h · migraine headache ‐ moderate or severe pain

The review found no eligible studies for this question.

1 finding from 1 review

Aspirin with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Sustained headache relief at 24 h · migraine headache ‐ moderate or severe pain

1 finding from 1 review

Aspirin with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1142 participants
Moderate

Intervention not reported

At least one AE · migraine headache ‐ moderate or severe pain

1 finding from 1 review

Aspirin with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1892 participants
Low

Intervention not reported

Serious AE · migraine headache ‐ moderate or severe pain

The review found no eligible studies for this question.

1 finding from 1 review

Aspirin with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Pain‐free at 2 h · adults with migraine headache ‐ moderate or severe pain

1 finding from 1 review

Diclofenac with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1447 participants
Moderate

Intervention not reported

Headache relief at 2 h · adults with migraine headache ‐ moderate or severe pain

1 finding from 1 review

Diclofenac with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1447 participants
Moderate

Intervention not reported

Sustained pain‐free at 24 h · adults with migraine headache ‐ moderate or severe pain

1 finding from 1 review

Diclofenac with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1578 participants
Moderate

Intervention not reported

Sustained headache relief at 24 h · adults with migraine headache ‐ moderate or severe pain

The review found no eligible studies for this question.

1 finding from 1 review

Diclofenac with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

At least one AE · adults with migraine headache ‐ moderate or severe pain

1 finding from 1 review

Diclofenac with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1075 participants
Low

Intervention not reported

Serious AE · adults with migraine headache ‐ moderate or severe pain

The review found no eligible studies for this question.

1 finding from 1 review

Diclofenac with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Naproxen 500 mg or 825 mg vs placebo

Pain‐free at 2 hours · migraine headache ‐ moderate or severe pain

1 finding from 1 review

Naproxen with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Naproxen 500 mg or 825 mg vs placebo

Headache relief at 2 h · migraine headache ‐ moderate or severe pain

1 finding from 1 review

Naproxen with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Naproxen 500 mg or 825 mg vs placebo

Sustained pain‐free at 24 h · migraine headache ‐ moderate or severe pain

1 finding from 1 review

Naproxen with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Naproxen 500 mg or 825 mg vs placebo

Sustained headache relief at 24 h · migraine headache ‐ moderate or severe pain

1 finding from 1 review

Naproxen with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Naproxen 500 mg or 825 mg vs placebo

Number of participants reporting an adverse event · migraine headache ‐ moderate or severe pain

1 finding from 1 review

Naproxen with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low