Findings

What do systematic reviews say?

3,097 questions · 3,266 findings · 631 reviews

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No studies found 430 · 13.2%GRADE not reported 193 · 5.9%Very low 995 · 30.5%Low 904 · 27.7%Moderate 591 · 18.1%High 153 · 4.7%

n3PUFAs vs placebo

Depressive symptomology (continuous) HDRS where possible; higher scores indicate greater symptomology · adults with Major Depressive Disorder

1 finding from 1 review

Omega‐3 fatty acids for depression in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
33 studies · 1848 participants
Very low

n3PUFAs vs placebo

Quality of lifeValidated quality of life scales as used by authors, CGI (7‐point scale) where possible, higher scores indicate poorer quality of life · adults with Major Depressive Disorder

1 finding from 1 review

Omega‐3 fatty acids for depression in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 476 participants
Very low

Interventions delivered by dental professionals vs control

Smoking cessation · participants who used tobacco products

It is very uncertain whether interventions delivered by dental professionals changes behavioural support from dental professional at high school/college… compared with control (very low certainty).

1 finding from 1 review

Interventions for tobacco cessation delivered by dental professionals 2021 · Cochrane Headline outcomes only
RR 1.51 [0.86, 2.65]
3 studies · 1020 participants
Very low

Phacoemulsification vs laser peripheral iridotomy

Quality of life measures(measured on the EQ‐5D; higher = better) (at 12 months) · participants with primary angle‐closure glaucoma

1 finding from 1 review

Lens extraction for chronic angle‐closure glaucoma 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Hydrophilic‐coated catheter vs uncoated catheter

Participant‐assessed outcome (satisfaction) (higher score = greater satisfaction)Scale from: 0 to 10 · long‐term bladder management

1 finding from 1 review

Intermittent catheter techniques, strategies and designs for managing long‐term bladder conditions 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 114 participants
Very low

Supported discharge and multidisciplinary home rehabilitation vs (Optimised) usual care

'Poor outcome' (dead or moved to higher level of care or unable to walk) · Older people undergoing hip fracture aftercare

It is very uncertain whether supported discharge and multidisciplinary home rehabilitation changes 'Poor outcome' (dead or moved to higher level of care or unable to… compared with usual care: mainly (very low certainty).

1 finding from 1 review

Multidisciplinary rehabilitation for older people with hip fractures 2021 · Cochrane Headline outcomes only
RR 0.91 [0.62, 1.35]
3 studies · 377 participants
Very low

Supported discharge and multidisciplinary home rehabilitation vs (Optimised) usual care

Permanent move to higher level of care (hostel, nursing home, sheltered housing) · Older people undergoing hip fracture aftercare

It is very uncertain whether supported discharge and multidisciplinary home rehabilitation changes permanent move to higher level of care (hostel, nursing home,… compared with usual care: mainly (very low certainty).

1 finding from 1 review

Multidisciplinary rehabilitation for older people with hip fractures 2021 · Cochrane Headline outcomes only
RR 0.35 [0.07, 1.69]
2 studies · 168 participants
Very low

Calf, quadriceps, and hamstring stretching vs no stretching

Cramp severity (0 to 10 VAS; higher = more pain) (after 6 weeks) · 50‐ to 60‐year‐old women with metabolic syndrome

1 finding from 1 review

Non‐drug therapies for the secondary prevention of lower limb muscle cramps 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
Very low

Calf and hamstring stretching vs no intervention

Change in cramp severity (0 to 10 VAS; higher = worse pain) (after 6 weeks) · older adults with lower limb muscle cramps

1 finding from 1 review

Non‐drug therapies for the secondary prevention of lower limb muscle cramps 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Low

Ultrasound‐guided injection vs non‐image‐guided injection

Function Various validated function scales. · Patients with shoulder pain

1 finding from 1 review

Image‐guided glucocorticoid injection versus injection without image guidance for shoulder pain 2021 · Cochrane Headline outcomes only
no estimate extracted
14 studies · 895 participants
Moderate

Ultrasound‐guided injection vs non‐image‐guided injection

Mean change in quality of life at ≥ 12 months using the 36‐Item Short Form Health Survey mental component score (SF‐36 MCS) · Patients with shoulder pain

1 finding from 1 review

Image‐guided glucocorticoid injection versus injection without image guidance for shoulder pain 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 220 participants
Low

Primary health professionals and lay health workers vs usual care

Carer burden, well‐being or quality of life · people with dementia and their carers

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 53 participants
Very low

Primary health professionals and lay health workers vs usual care

Functional impairment · people with dementia and their carers

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 81 participants
Very low

Lay health worker‐led psychosocial interventions vs usual care or no treatment

Depressive symptoms · children/adolescents with post‐traumatic stress and related depressive/anxiety symptoms

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1092 participants
Moderate

Lay health worker‐led psychosocial interventions vs usual care or no treatment

Severity of PTSD symptoms · children/adolescents with post‐traumatic stress and related depressive/anxiety symptoms

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1090 participants
Low

Lay health worker‐led psychosocial interventions vs usual care or no treatment

Functional impairment · children/adolescents with post‐traumatic stress and related depressive/anxiety symptoms

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1092 participants
Moderate

Primary‐level worker‐led collaborative care vs usual care

Quality of life ‐ intermediate term (1 to 6 months post intervention) EQ‐5Di; SF‐36c,m; WHOQOL‐BREFe,j,n (higher score = better quality of life) · adults with common mental disorders

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 2199 participants
Low

Community professional‐led interventions vs no care

Severity of PTSD symptoms · children/adolescents with post‐traumatic stress and related depressive/anxiety symptoms

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 679 participants
Very low

Community professional‐led interventions vs no care

Depression symptoms (1 to 6 months post intervention) Beck Depression Inventorye; Oxford Measure of Psychosocial Adjustmentd (higher score = higher severity) · children/adolescents with post‐traumatic stress and related depressive/anxiety symptoms

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 602 participants
Low

Community professional‐led interventions vs no care

Functional impairment · children/adolescents with post‐traumatic stress and related depressive/anxiety symptoms

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 602 participants
Very low