Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,320 questions · 4,561 findings · 388 reviews

No studies found 1,138 · 25%GRADE not reported 886 · 19.4%Very low 1,014 · 22.2%Low 849 · 18.6%Moderate 543 · 11.9%High 131 · 2.9%

Cognitive behavioural (group psychotherapy) therapy vs Placebo pill

Improvement in burning mouth symptoms · Adults over 18 years of age with chronic orofacial pain (burning mouth syndrome)

Cognitive behavioural (group psychotherapy) therapy showed no clear difference in improvement in burning mouth symptoms compared with placebo pill; GRADE not reported.

1 finding from 1 review

Flossing plus toothbrushing (self-performed; manual or automated floss) vs Toothbrushing alone

Economic and resource cost of flossing · Dentate adults aged 16 years or older (excluding orthodontic patients and those with severe periodontal disease)

The review found no eligible studies for this question.

1 finding from 1 review

Flossing plus toothbrushing (self-performed; manual or automated floss) vs Toothbrushing alone

Interproximal caries · Dentate adults aged 16 years or older (excluding orthodontic patients and those with severe periodontal disease)

The review found no eligible studies for this question.

1 finding from 1 review

Flossing plus toothbrushing (self-performed; manual or automated floss) vs Toothbrushing alone

Periodontitis (clinical attachment loss) · Dentate adults aged 16 years or older (excluding orthodontic patients and those with severe periodontal disease)

The review found no eligible studies for this question.

1 finding from 1 review

Psychosocial interventions (cognitive behavioural therapy, biofeedback, combination CBT/biofeedback, physical self-regulation/posture self-control) vs usual care

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adults over 18 years of age with chronic orofacial pain (temporomandibular disorder (TMD))

Psychosocial interventions (cognitive behavioural therapy,… led to lower pain intensity (long term) compared with usual care (conservative treatment: education, counselling,…; GRADE not reported.

1 finding from 1 review

Psychosocial interventions (cognitive behavioural therapy, biofeedback, combination CBT/biofeedback, physical self-regulation/posture self-control) vs usual care

Muscle palpation pain (long term) · Adults over 18 years of age with chronic orofacial pain (temporomandibular disorder (TMD))

Psychosocial interventions (cognitive behavioural therapy,… showed no clear difference in muscle palpation pain (long term) compared with usual care (conservative treatment: education, counselling,…; GRADE not reported.

1 finding from 1 review
  • Psychosocial interventions for the management of chronic orofacial pain 2011 · Cochrane All outcomes
    Long term (more than 3 months)
    Muscle palpation pain long term (greater than 3 months): 3 studies; results not pooled owing to substantial heterogeneity (I2=64%); insufficient evidence to draw conclusions for any individual intervention. One study…
    3 studies
    GRADE not reported

Habit reversal vs waiting list control

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adults over 18 years of age with chronic orofacial pain (temporomandibular disorder (TMD))

Habit reversal led to lower pain intensity (short term / post-treatment) compared with waiting list control; GRADE not reported.

1 finding from 1 review

Flossing plus toothbrushing (self-performed; manual or automated floss) vs Toothbrushing alone

Bad breath (halitosis) · Dentate adults aged 16 years or older (excluding orthodontic patients and those with severe periodontal disease)

The review found no eligible studies for this question.

1 finding from 1 review

Psychosocial interventions (cognitive behavioural therapy, biofeedback, combination CBT/biofeedback, physical self-regulation/posture self-control) vs usual care

Depression (long term) · Adults over 18 years of age with chronic orofacial pain (temporomandibular disorder (TMD))

Psychosocial interventions (cognitive behavioural therapy,… led to lower depression (long term) compared with usual care (conservative treatment: education, counselling,…; GRADE not reported.

1 finding from 1 review

Flossing plus toothbrushing (self-performed; manual or automated floss) vs Toothbrushing alone

Calculus · Dentate adults aged 16 years or older (excluding orthodontic patients and those with severe periodontal disease)

The review found no eligible studies for this question.

1 finding from 1 review

Flossing plus toothbrushing (self-performed; manual or automated floss) vs Toothbrushing alone

Quality of life · Dentate adults aged 16 years or older (excluding orthodontic patients and those with severe periodontal disease)

The review found no eligible studies for this question.

1 finding from 1 review

Cognitive behaviour therapy vs Attention placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adults over 18 years of age with chronic orofacial pain (burning mouth syndrome)

Cognitive (behavioural) therapy led to lower burning mouth pain intensity (6-month follow-up) compared with attention placebo; GRADE not reported.

1 finding from 1 review

Cognitive behaviour therapy vs Attention placebo

Burning mouth pain intensity (post-treatment) · Adults over 18 years of age with chronic orofacial pain (burning mouth syndrome)

Cognitive (behavioural) therapy led to lower burning mouth pain intensity (post-treatment) compared with attention placebo; GRADE not reported.

1 finding from 1 review

Psychosocial interventions (cognitive behavioural therapy, biofeedback, combination CBT/biofeedback, physical self-regulation/posture self-control) vs usual care

Reduction in pain intensity · Adults over 18 years of age with chronic orofacial pain (temporomandibular disorder (TMD))

Psychosocial interventions (cognitive behavioural therapy,… led to higher pain intensity (short term) compared with usual care (conservative treatment: education, counselling,…; GRADE not reported.

1 finding from 1 review

Psychosocial interventions (cognitive behavioural therapy, biofeedback, combination CBT/biofeedback, physical self-regulation/posture self-control) vs usual care

Pain severity - impact: activity interference / disability (long term) · Adults over 18 years of age with chronic orofacial pain (temporomandibular disorder (TMD))

Psychosocial interventions (cognitive behavioural therapy,… led to lower pain severity - impact: activity interference / disability (long term) compared with usual care (conservative treatment: education, counselling,…; GRADE not reported.

1 finding from 1 review

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

Quality of life (validated questionnaire) · Children or adolescents aged 3 years or older with velopharyngeal insufficiency (VPI) associated with non-syndromic submucous cleft palate

The review found no eligible studies for this question.

1 finding from 1 review