Macrolides vs placebo
Health‐related quality of life (AQLQ)Scale from: 1‐7 (higher is better) · adults and children with chronic asthma
1 finding from 1 review
- no estimate extracted6 studies · 802 participantsVery low
Findings
What do systematic reviews say?
3,006 questions · 3,171 findings · 607 reviews · Headline outcomes only
No studies found 411 · 13%GRADE not reported 153 · 4.8%Very low 968 · 30.5%Low 897 · 28.3%Moderate 589 · 18.6%High 153 · 4.8%
Intervention not reported
Cohort studies ‐ autism risk (moderate/high), MMR · children 9 months to 15 years old
The intervention may leads to lower cohort studies ‐ autism risk (moderate/high), MMR (low certainty).
1 finding from 1 review
- Vaccines for measles, mumps, rubella, and varicella in children 2021 · Cochrane Headline outcomes onlyRate ratio 0.8 [0.64, 0.98]1 study · 1914 participantsLow
n3PUFAs vs placebo
Depressive symptomology (continuous) HDRS where possible; higher scores indicate greater symptomology · adults with Major Depressive Disorder
1 finding from 1 review
- no estimate extracted33 studies · 1848 participantsVery low
n3PUFAs vs placebo
Quality of lifeValidated quality of life scales as used by authors, CGI (7‐point scale) where possible, higher scores indicate poorer quality of life · adults with Major Depressive Disorder
1 finding from 1 review
- no estimate extracted12 studies · 476 participantsVery low
Interventions delivered by dental professionals vs control
Smoking cessation · participants who used tobacco products
It is very uncertain whether interventions delivered by dental professionals changes behavioural support from dental professional at high school/college… compared with control (very low certainty).
1 finding from 1 review
- Interventions for tobacco cessation delivered by dental professionals 2021 · Cochrane Headline outcomes onlyRR 1.51 [0.86, 2.65]3 studies · 1020 participantsVery low
Phacoemulsification vs laser peripheral iridotomy
Quality of life measures(measured on the EQ‐5D; higher = better) (at 12 months) · participants with primary angle‐closure glaucoma
1 finding from 1 review
- no estimate extractedStudies not reportedModerate
Hydrophilic‐coated catheter vs uncoated catheter
Participant‐assessed outcome (satisfaction) (higher score = greater satisfaction)Scale from: 0 to 10 · long‐term bladder management
1 finding from 1 review
- Intermittent catheter techniques, strategies and designs for managing long‐term bladder conditions 2021 · Cochrane Headline outcomes onlyno estimate extracted1 study · 114 participantsVery low
Supported discharge and multidisciplinary home rehabilitation vs (Optimised) usual care
'Poor outcome' (dead or moved to higher level of care or unable to walk) · Older people undergoing hip fracture aftercare
It is very uncertain whether supported discharge and multidisciplinary home rehabilitation changes 'Poor outcome' (dead or moved to higher level of care or unable to… compared with usual care: mainly (very low certainty).
1 finding from 1 review
- Multidisciplinary rehabilitation for older people with hip fractures 2021 · Cochrane Headline outcomes onlyRR 0.91 [0.62, 1.35]3 studies · 377 participantsVery low
Supported discharge and multidisciplinary home rehabilitation vs (Optimised) usual care
Permanent move to higher level of care (hostel, nursing home, sheltered housing) · Older people undergoing hip fracture aftercare
It is very uncertain whether supported discharge and multidisciplinary home rehabilitation changes permanent move to higher level of care (hostel, nursing home,… compared with usual care: mainly (very low certainty).
1 finding from 1 review
- Multidisciplinary rehabilitation for older people with hip fractures 2021 · Cochrane Headline outcomes onlyRR 0.35 [0.07, 1.69]2 studies · 168 participantsVery low
Calf, quadriceps, and hamstring stretching vs no stretching
Cramp severity (0 to 10 VAS; higher = more pain) (after 6 weeks) · 50‐ to 60‐year‐old women with metabolic syndrome
1 finding from 1 review
- Non‐drug therapies for the secondary prevention of lower limb muscle cramps 2021 · Cochrane Headline outcomes onlyno estimate extracted1 study · 24 participantsVery low
Calf and hamstring stretching vs no intervention
Change in cramp severity (0 to 10 VAS; higher = worse pain) (after 6 weeks) · older adults with lower limb muscle cramps
1 finding from 1 review
- Non‐drug therapies for the secondary prevention of lower limb muscle cramps 2021 · Cochrane Headline outcomes onlyno estimate extracted1 study · 80 participantsLow
Ultrasound‐guided injection vs non‐image‐guided injection
Function Various validated function scales. · Patients with shoulder pain
1 finding from 1 review
- Image‐guided glucocorticoid injection versus injection without image guidance for shoulder pain 2021 · Cochrane Headline outcomes onlyno estimate extracted14 studies · 895 participantsModerate
Ultrasound‐guided injection vs non‐image‐guided injection
Mean change in quality of life at ≥ 12 months using the 36‐Item Short Form Health Survey mental component score (SF‐36 MCS) · Patients with shoulder pain
1 finding from 1 review
- Image‐guided glucocorticoid injection versus injection without image guidance for shoulder pain 2021 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 220 participantsLow
Primary health professionals and lay health workers vs usual care
Carer burden, well‐being or quality of life · people with dementia and their carers
1 finding from 1 review
- Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes onlyno estimate extracted1 study · 53 participantsVery low
Primary health professionals and lay health workers vs usual care
Functional impairment · people with dementia and their carers
1 finding from 1 review
- Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes onlyno estimate extracted1 study · 81 participantsVery low
Lay health worker‐led psychosocial interventions vs usual care or no treatment
Depressive symptoms · children/adolescents with post‐traumatic stress and related depressive/anxiety symptoms
1 finding from 1 review
- Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 1092 participantsModerate
Lay health worker‐led psychosocial interventions vs usual care or no treatment
Severity of PTSD symptoms · children/adolescents with post‐traumatic stress and related depressive/anxiety symptoms
1 finding from 1 review
- Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 1090 participantsLow
Lay health worker‐led psychosocial interventions vs usual care or no treatment
Functional impairment · children/adolescents with post‐traumatic stress and related depressive/anxiety symptoms
1 finding from 1 review
- Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 1092 participantsModerate
Primary‐level worker‐led collaborative care vs usual care
Quality of life ‐ intermediate term (1 to 6 months post intervention) EQ‐5Di; SF‐36c,m; WHOQOL‐BREFe,j,n (higher score = better quality of life) · adults with common mental disorders
1 finding from 1 review
- Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes onlyno estimate extracted6 studies · 2199 participantsLow
Community professional‐led interventions vs no care
Severity of PTSD symptoms · children/adolescents with post‐traumatic stress and related depressive/anxiety symptoms
1 finding from 1 review
- Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 679 participantsVery low