Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,245 questions · 1,274 findings · 321 reviews

No studies found 247 · 19.4%GRADE not reported 195 · 15.3%Very low 372 · 29.2%Low 282 · 22.1%Moderate 141 · 11.1%High 37 · 2.9%

Less intensive vs more intensive follow‐up after primary cancer treatment

Depression · adult cancer survivors from the following cancer sites: breast, colorectal, head‐and‐neck, Hodgkin lymphoma, melanoma, non‐small cell lung…

The review found no eligible studies for this question.

1 finding from 1 review

Less intensive vs more intensive follow‐up after primary cancer treatment

Overall survival · adult cancer survivors from the following cancer sites: breast, colorectal, head‐and‐neck, Hodgkin lymphoma, melanoma, non‐small cell lung…

Less intensive showed no clear difference in overall survival compared with more intensive follow‐up after primary cancer treatment (low certainty).

1 finding from 1 review

Less intensive vs more intensive follow‐up after primary cancer treatment

Time to detection of recurrence · adult cancer survivors from the following cancer sites: breast, colorectal, head‐and‐neck, Hodgkin lymphoma, melanoma, non‐small cell lung…

Less intensive probably leads to lower time to detection of recurrence compared with more intensive follow‐up after primary cancer treatment (moderate certainty).

1 finding from 1 review

Mobilization of community first responders (CFRs) in addition to routine emergency medical services (EMS) care vs routine EMS care

Neurological function at hospital discharge, measured by cerebral performance category (CPC) · adults and children more than 4 weeks old suffering from OHCA

The review found no eligible studies for this question.

1 finding from 1 review

Mobilization of community first responders (CFRs) in addition to routine emergency medical services (EMS) care vs routine EMS care

Neurological function at 30 days, measured by cerebral performance category (CPC) · adults and children more than 4 weeks old suffering from OHCA

The review found no eligible studies for this question.

1 finding from 1 review

Miswak (Salvadora persica) stick vs Chlorhexidine mouthwash

Patient self-assessment VAS (scale 0 to 10) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

It is very uncertain whether miswak (Salvadora persica) stick changes patient self-assessment VAS (scale 0 to 10) compared with chlorhexidine mouthwash (very low certainty).

1 finding from 1 review

Chlorine dioxide mouthrinse (with tongue scraping) vs Chlorhexidine mouthwash (with tongue scraping)

VSC: hydrogen sulphide · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

Chlorine dioxide mouthrinse (with tongue scraping) showed no clear difference in VSC: hydrogen sulphide compared with chlorhexidine mouthwash (with tongue scraping); GRADE not reported.

1 finding from 1 review

Protease cysteine + actinidine tablets vs placebo (3 tablets/4 times a day

Volatile sulphur compounds (VSC), gas chromatography · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

Protease cysteine + actinidine tablets showed no clear difference in volatile sulphur compounds (VSC), OralChroma compared with placebo tablets; GRADE not reported.

1 finding from 1 review

Triclosan/copolymer-containing fluoride toothpaste vs Non-fluoride (0 ppm F) placebo toothpaste

Volatile sulphur compounds (VSC), gas chromatography · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    Niles 1999 (cross-over trial) compared 0.3% triclosan + 2.0% PVM/MA + 0.243% NaF toothpaste versus placebo toothpaste; VSC by gas chromatograph. We could not use the results in the meta-analysis as there was no…
    1 study
    GRADE not reported

Chlorine dioxide mouthrinse (with tongue scraping) vs Chlorhexidine mouthwash (with tongue scraping)

Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    1 week
    Wirthlin 2011 reported altered taste sensation as the adverse event. OLT scores could not be included in the analysis as the group-wise data were not given.
    1 study · 22 participants
    GRADE not reported