Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,543 questions · 2,589 findings · 168 reviews · Schizophrenia

No studies found 601 · 23.2%GRADE not reported 446 · 17.2%Very low 721 · 27.8%Low 505 · 19.5%Moderate 274 · 10.6%High 42 · 1.6%

HALOPERIDOL vs chlorpromazine

Tranquil or asleep: Not tranquil or asleep · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes tranquillisation or asleep Not tranquil or asleep compared with OTHER ANTIPSYCHOTIC: b. CHLORPROMAZINE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs COMBINATIONS: d. QUETIAPINE + MAGNESIUM VALPROATE

Specific behaviour ‐ agitation · patients with psychosis‐induced aggression or agitation
2 findings from 1 review

HALOPERIDOL vs chlorpromazine

Repeated need for rapid tranquillisation ‐ more than 1 injection · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes repeated need for rapid tranquillisation ‐ more that 1 injection compared with OTHER ANTIPSYCHOTIC: b. CHLORPROMAZINE (very low certainty).

1 finding from 1 review