Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,268 questions · 1,343 findings · 197 reviews

No studies found 317 · 23.6%GRADE not reported 189 · 14.1%Very low 356 · 26.5%Low 271 · 20.2%Moderate 173 · 12.9%High 37 · 2.8%

Laparoscopic colposuspension vs open colposuspension

Subjective cure within 18 months: laparoscopic colposuspension using sutures · women with urinary incontinence

Laparoscopic colposuspension showed no clear difference in subjective cure within 18 months: laparoscopic colposuspension using… compared with open colposuspension (high certainty).

1 finding from 1 review

Laparoscopic colposuspension vs open colposuspension

Subjective cure within 18 months: laparoscopic colposuspension using mesh and staples · women with urinary incontinence

It is very uncertain whether laparoscopic colposuspension changes subjective cure within 18 months: laparoscopic colposuspension using… compared with open colposuspension (very low certainty).

1 finding from 1 review

Laparoscopic colposuspension vs open colposuspension

Adverse effects: de novo detrusor overactivity (urodynamic diagnosis) · women with urinary incontinence

Laparoscopic colposuspension showed no clear difference in adverse effects: de novo detrusor overactivity (urodynamic diagnosis) compared with open colposuspension (moderate certainty).

1 finding from 1 review

Lithium vs Zuclopenthixol (Cis Z/Trans E isomer)

Efficacy: response (categorical) BMRS change ≥ 50% from baseline to end of study · acute mania

It is very uncertain whether lithium changes efficacy: response (categorical) BMRS change ≥ 50% from baseline to… compared with zuclopenthixol (very low certainty).

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    OR 1.33 [0.3, 5.91]
    1 study · 28 participants
    Very low

Lithium vs Zuclopenthixol (Cis Z/Trans E isomer)

Efficacy: response (continuous) change in BPRS (total) from baseline to end of study ‐all data · acute mania

The review found no eligible studies for this question.

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Lithium vs Zuclopenthixol (Cis Z/Trans E isomer)

Acceptability: total withdrawals · acute mania

It is very uncertain whether lithium changes acceptability: total withdrawals compared with zuclopenthixol (very low certainty).

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    OR 0.78 [0.17, 3.49]
    1 study · 28 participants
    Very low