Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,340 questions · 1,512 findings · 205 reviews

No studies found 317 · 21%GRADE not reported 358 · 23.7%Very low 356 · 23.5%Low 271 · 17.9%Moderate 173 · 11.4%High 37 · 2.4%

Pulpotomy (full or partial) vs None (single-arm pooled success proportion)

Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis and open (immature) root apex due to carious pulp exposure

In open-apex teeth, pooled pulpotomy success was 95.8% (95% CI 81-99%); significantly higher than closed apex (z=2.33, p=0.02); ungraded.

1 finding from 1 review

Endometrial resection or ablation vs open hysterectomy

Effectiveness Proportion of women with perception of improvement of bleeding symptoms · HMB

Endometrial resection or ablation probably leads to lower effectiveness Woman's perception (proportion with improvement in… compared with open hysterectomy (moderate certainty).

1 finding from 1 review

Intervention not reported

Antibiotics prior to long‐term CVC insertion versus control: catheter‐related infections · adults and children diagnosed with an oncologic disease with a newly‐inserted long‐term CVC who were at risk of neutropenia due to…

The intervention showed no clear difference in antibiotics prior to long‐term CVC insertion versus control:… (moderate certainty).

1 finding from 1 review

Intervention not reported

Antibiotic versus heparin only lock/flush solution: catheter‐related infections · adults and children diagnosed with an oncologic disease with a newly‐inserted long‐term CVC who were at risk of neutropenia due to…

The intervention probably leads to lower antibiotic versus heparin only lock/flush solution: catheter‐related… (moderate certainty).

1 finding from 1 review

Percutaneous patellar osteosynthesis vs open surgery

Observer‐rated measures of knee function Knee function scores (see comment) · adults with fractures of the patella

It is very uncertain whether percutaneous patellar osteosynthesis changes observer‐rated measures of knee function Knee function scores (see… compared with open surgery (very low certainty).

1 finding from 1 review

Chloral hydrate oral (50 mg/kg) vs sodium thiopental rectal (25 mg/kg)

Proportion of children who successfully completed neurodiagnostic procedure without interruption by the child awakening · children undergoing neurodiagnostic procedures

Chloral hydrate oral (50 mg/kg) showed no clear difference in proportion of children who successfully completed neurodiagnostic… compared with sodium thiopental rectal (25 mg/kg) (moderate certainty).

1 finding from 1 review