Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,230 questions · 1,303 findings · 326 reviews · Headline outcomes only

No studies found 73 · 5.6%GRADE not reported 21 · 1.6%Very low 497 · 38.1%Low 403 · 30.9%Moderate 245 · 18.8%High 64 · 4.9%

Physiotherapy and occupational therapy vs placebo

Short‐term (1 week) change in quality of life scores related to communication as measured by validated communication assessments Functional Independence Measure (total). Scale from: 0 to 126. Higher scores indicate less disability · people with speech disorder resulting from hereditary ataxias
1 finding from 1 review

Betamethasone vs placebo

Short‐term (within 1 month) change in isolated movement, objective and subjective measures of speech production Cooper 2008 reported 3 speech measures: ICARS speech subscale. Scale from: 0 to 8. Higher scores indicate greater clinical severity Syl... · people with speech disorder resulting from hereditary ataxias
1 finding from 1 review

High‐dose vs low‐dose coenzyme Q10 and vitamin E

Short‐term (within 1 month) change in isolated movement, objective and subjective measures of speech production Cooper 2008 reported 3 speech measures: ICARS speech subscale. Scale from: 0 to 8. Higher scores indicate greater clinical severity Syl... · people with speech disorder resulting from hereditary ataxias
1 finding from 1 review

Yoga in addition to standard care vs standard‐of‐care therapy

Distress at · participants with haematological malignancies

It is very uncertain whether yoga in addition to standard care changes distress Scale from: 0 to 75. Higher scores indicate a more severe… compared with standard care only (very low certainty).

1 finding from 1 review