Change in disability score (3 point‐change) · children with SMA type II
Intrathecal injected nusinersen showed no clear difference in change in disability score (3 point‐change) compared with sham procedure (moderate certainty).
1 finding from 1 review
Muscle strength · children with SMA type II
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Acquiring the ability to stand or walk · children with SMA type II
Intrathecal injected nusinersen showed no clear difference in acquiring the ability to stand or walk compared with sham procedure (low certainty).
1 finding from 1 review
Change in quality of life · children with SMA type II
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in pulmonary function · children with SMA type II
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Acquiring the ability to stand or walk · children with SMA types II and III
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in disability score · non‐ambulatory children and adolescents with SMA types II and III
4 findings from 1 review
no estimate extracted
1 study · 160 participants
Very low
no estimate extracted
1 study · 160 participants
Very low
RR 1.43
1 study · 160 participants
Very low
Show 1 more finding
Muscle strength · non‐ambulatory children and adolescents with SMA types II and III
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Acquiring the ability to stand or walk · non‐ambulatory children and adolescents with SMA types II and III
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in quality of life · non‐ambulatory children and adolescents with SMA types II and III
1 finding from 1 review
Change in pulmonary function · non‐ambulatory children and adolescents with SMA types II and III
1 finding from 1 review
Change in quality of life · children with SMA types II and III
1 finding from 1 review
Change in disability score · children with SMA type II
1 finding from 1 review
Muscle strength · children with SMA type II
1 finding from 1 review
Acquiring the ability to stand or walk · children with SMA type II
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in quality of life · children with SMA type II
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in pulmonary function · children with SMA type II
1 finding from 1 review
Change in disability score · children and adults with SMA types II and III
1 finding from 1 review
no estimate extracted
19 participants
Very low
Muscle strength · children and adults with SMA types II and III
1 finding from 1 review
no estimate extracted
19 participants
Low
Change in pulmonary function · children with SMA types II and III
1 finding from 1 review