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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,463 questions in 125 reviews · Anaesthesia
current versionsNo studies 197 · 13.5%Ungraded 203 · 13.9%Very low 307 · 21%Low 441 · 30.1%Moderate 245 · 16.7%High 70 · 4.8%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intervention NR Dimenhydrinate (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Meclizine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Promethazine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Dolasetron (5 RCTs; 400 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 5 studies · 400 participants | Low |
Intervention NR Dexamethasone (43 RCTs; 4804 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 43 studies · 4804 participants | High |
Intervention NR Anticholinergics · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Scopolamine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Comparator · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Placebo · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Total studies: 32 RCTs Total participants: 4369 Number of treatments: 10 Geometry of the network** · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 32 studies · 4369 participants | Ungraded |
Intervention NR Dolasetron (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Granisetron (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Ondansetron (no direct evidence, indirect evidence only) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | Very low |
Intervention NR Palonosetron (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Ramosetron (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Methylprednisolone (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Tropisetron (1 RCT; 156 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 study · 156 participants | Low |
Intervention NR D2 receptor antagonists · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 2 participants | Ungraded |
Intervention NR Amisulpride (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Droperidol (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Haloperidol (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Metoclopramide (1 RCT; 104 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 study · 104 participants | Very low |
Intervention NR Perphenazine (0 RCT; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR NK1 receptor antagonists · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 participants | Ungraded |
Intervention NR Aprepitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Casopitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Antihistamines · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Fosaprepitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Rolapitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Corticosteroids · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Dexamethasone (24 RCTs; 3199 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 24 studies · 3199 participants | Very low |
Intervention NR Methylprednisolone (1 RCT; 40 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 study · 40 participants | Very low |
Intervention NR Antihistamines · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Dimenhydrinate (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Meclizine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Promethazine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Anticholinergics · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Dimenhydrinate (1 RCT; 56 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 study · 56 participants | Very low |
Intervention NR Scopolamine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Comparator · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Placebo · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Total studies: 25 RCTs Total participants: 5067 Number of treatments: 18 Geometry of the network** · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 25 studies · 5067 participants | Ungraded |
Intervention NR Dolasetron (2 RCTs; 1184 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 2 studies · 1184 participants | Low |
Intervention NR Granisetron (1 RCT; 50 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 study · 50 participants | Very low |
Intervention NR Ondansetron (4 RCTs; 1643 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 4 studies · 1643 participants | Very low |
Intervention NR Palonosetron (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Ramosetron (1 RCT; 140 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 study · 140 participants | Low |
Intervention NR Tropisetron (1 RCT; 50 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 study · 50 participants | Very low |
Intervention NR Meclizine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR D2 receptor antagonists · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 2 participants | Ungraded |