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What do systematic reviews say?

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Evidence found and GRADE certainty

259 questions · 271 findings · 11 reviews · Temporomandibular disorders and sleep

No studies found 70 · 25.8%GRADE not reported 160 · 59%Very low 29 · 10.7%Low 12 · 4.4%Moderate 0 · 0%High 0 · 0%

CBT vs alternative treatment

Adverse events · People aged 12 years and over with painful TMD lasting 3 months or longer
1 finding from 1 review
  • SoF: 3 studies reported minor adverse events in the control group; 1 study reported minor adverse events in psychological therapy group; 1 study reported that there were no adverse events. Results: NCT00066937 minor…
    5 studies
    Very low

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Daytime symptom: thirstiness in the morning (questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)

Oral appliance or functional orthopaedic appliance showed no clear difference in daytime symptom: thirstiness in the morning (questionnaire) compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Reduction of apnoea episodes (apnoea-hypopnoea index) · Children with obstructive sleep apnoea (aged 15 years or younger)

It is very uncertain whether oral appliance or functional orthopaedic appliance changes reduction of apnoea episodes (apnoea-hypopnoea index) compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Nocturnal symptom: nightmares (questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)

Oral appliance or functional orthopaedic appliance showed no clear difference in nocturnal symptom: nightmares (questionnaire) compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Tiredness · Children with obstructive sleep apnoea (aged 15 years or younger)

It is very uncertain whether oral appliance or functional orthopaedic appliance changes daytime symptom: tiredness (Brouillette questionnaire) compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Nocturnal symptom: habitual snoring (questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)

It is very uncertain whether oral appliance or functional orthopaedic appliance changes nocturnal symptom: habitual snoring (questionnaire) compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Side effects / tolerability · Children with obstructive sleep apnoea (aged 15 years or younger)
1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Daytime symptom: sleepiness (Brouillette questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)

It is very uncertain whether oral appliance or functional orthopaedic appliance changes daytime symptom: sleepiness (Brouillette questionnaire) compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Irritability · Children with obstructive sleep apnoea (aged 15 years or younger)

It is very uncertain whether oral appliance or functional orthopaedic appliance changes daytime symptom: irritability (Brouillette questionnaire) compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Reduction of upper airway resistance syndrome (UARS) and body-weight/BMI development (polysomnography) · Children with obstructive sleep apnoea (aged 15 years or younger)

The review found no eligible studies for this question.

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Daytime symptom: morning headache (Brouillette questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)

It is very uncertain whether oral appliance or functional orthopaedic appliance changes daytime symptom: morning headache (Brouillette questionnaire) compared with placebo or no treatment (very low certainty).

1 finding from 1 review