Recurrent seizure at 18 months · children with febrile seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Recurrent seizure at 24 months · children with febrile seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Recurrent seizure at 36 months · children with febrile seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Recurrent seizure at 48 months · children with febrile seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Recurrent seizure at 60 months or greater · children with febrile seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of responders (at least 50% seizure frequency reduction in myoclonic seizures) · people with juvenile myoclonic epilepsy
It is very uncertain whether topiramate changes proportion of responders (at least 50% seizure frequency reduction… compared with valproate (very low certainty).
1 finding from 1 review
Proportion of responders (at least 50% seizure frequency reduction in PGTCS) · people with juvenile myoclonic epilepsy
It is very uncertain whether topiramate changes proportion of responders (at least 50% seizure frequency reduction… compared with valproate (very low certainty).
1 finding from 1 review
Proportion of participants who experienced at least one AE and individual AEs · people with juvenile myoclonic epilepsy
1 finding from 1 review
Seizure freedom · people with juvenile myoclonic epilepsy
It is very uncertain whether topiramate changes number of participants who were seizure‐free compared with valproate (very low certainty).
1 finding from 1 review
Efficacy: remission (categorical) YMRS ≤ 12 and no increase in MADRS at end of study · acute mania
Lithium showed no clear difference in efficacy: remission (categorical) YMRS ≤ 12 and no increase in MADRS… compared with valproate (moderate certainty).
1 finding from 1 review
Acceptability: total withdrawals · acute mania
Lithium showed no clear difference in acceptability: total withdrawals compared with valproate (high certainty).
1 finding from 1 review
Adverse event: tremor · acute mania
Lithium leads to higher adverse event: tremor compared with valproate (high certainty).
1 finding from 1 review
Somnolence · acute mania
Lithium leads to lower adverse event: somnolence compared with valproate (high certainty).
1 finding from 1 review
Nausea · acute mania
Lithium showed no clear difference in adverse event: nausea compared with valproate (moderate certainty).
1 finding from 1 review
Efficacy: response (categorical) YMRS/SADS‐C decrease ≥ 50% by end of study · acute mania
Lithium showed no clear difference in efficacy: response (categorical) YMRS/SADS‐C decrease ≥ 50% by end… compared with valproate (moderate certainty).
1 finding from 1 review
Efficacy: response (continuous) Change in YMRS (ITT‐LOCF) from baseline to end of study · acute mania
1 finding from 1 review
Tranquillisation or asleep ‐ not reported · psychosis‐induced aggression or agitation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Repeated need for tranquillisation ‐ not reported · psychosis‐induced aggression or agitation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Specific behaviour ‐ agitation · psychosis‐induced aggression or agitation
1 finding from 1 review
Global outcome · psychosis‐induced aggression or agitation
It is very uncertain whether HALOPERIDOL changes global outcome compared with COMBINATIONS: f. OLANZAPINE + MAGNESIUM VALPROATE (very low certainty).
1 finding from 1 review