Findings

What do systematic reviews say?

84 questions · 86 findings · 6 reviews

No studies found 14 · 16.3%GRADE not reported 1 · 1.2%Very low 3 · 3.5%Low 23 · 26.7%Moderate 30 · 34.9%High 15 · 17.4%

Failure (overall) · HIV‐infected adult patients treated with a PI‐containing regimen with undetectable viral load

The intervention showed no clear difference in failure (overall) (moderate certainty).

1 finding from 1 review

Abacavir‐based triple nucleoside regimens for maintenance therapy in patients with HIV 2013 · Cochrane Headline outcomes only
RR 0.88 [0.74, 1.04]
8 studies · 1606 participants
Moderate

Discontinuation for adverse events · HIV‐infected adult patients treated with a PI‐containing regimen with undetectable viral load

The intervention showed no clear difference in discontinuation for adverse events (moderate certainty).

1 finding from 1 review

Abacavir‐based triple nucleoside regimens for maintenance therapy in patients with HIV 2013 · Cochrane Headline outcomes only
RR 0.68 [0.44, 1.07]
8 studies · 1597 participants
Moderate

Virologic failure · HIV‐infected adult patients treated with a PI‐containing regimen with undetectable viral load

The intervention showed no clear difference in virologic failure (moderate certainty).

1 finding from 1 review

Abacavir‐based triple nucleoside regimens for maintenance therapy in patients with HIV 2013 · Cochrane Headline outcomes only
RR 1.39 [0.95, 2.02]
8 studies · 1587 participants
Moderate

Death and AIDS related events · HIV‐infected adult patients treated with a PI‐containing regimen with undetectable viral load

The intervention showed no clear difference in death and AIDS related events (low certainty).

1 finding from 1 review

Abacavir‐based triple nucleoside regimens for maintenance therapy in patients with HIV 2013 · Cochrane Headline outcomes only
RR 1.66 [0.62, 4.42]
4 studies · 1044 participants
Low