Cochrane · systematic review · CD008270
Abacavir‐based triple nucleoside regimens for maintenance therapy in patients with HIV
Cruciani, M, Mengoli, C, Serpelloni, G, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
HIV/AIDSAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 25%Moderate 3 · 75%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: HIV‐infected adult patients treated with a PI‐containing regimen with undetectable viral load
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Failure (overall) | RR 0.88 [0.74, 1.04] | 8 studies · 1606 participants | Moderate |
Discontinuation for adverse events | RR 0.68 [0.44, 1.07] | 8 studies · 1597 participants | Moderate |
Virologic failure | RR 1.39 [0.95, 2.02] | 8 studies · 1587 participants | Moderate |
Death and AIDS related events | RR 1.66 [0.62, 4.42] | 4 studies · 1044 participants | Low |