Adverse effects: 1. Sedation · patients with motion sickness
It is very uncertain whether antihistamines changes adverse effects: sedation Assessed by: self‐reported compared with scopolamine (very low certainty).
1 finding from 1 review
Adverse effects: sedation, impaired cognitive function, blurred vision · patients with motion sickness
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects: 1. Sedation · patients with motion sickness
Antihistamines may leads to higher adverse effects: sedation Assessed by: adverse effect questionnaire… compared with placebo (low certainty).
1 finding from 1 review
Proportion of children who had sedation failure after 1 dose of sedative agent · children undergoing neurodiagnostic procedures
Chloral hydrate oral (75 mg/kg) may leads to higher proportion of children who had sedation failure after 1 dose of… compared with pentobarbital intravenous (5 mg/kg) (low certainty).
1 finding from 1 review
Proportion of children who had sedation failure after 2 doses of sedative agent (same or different) · children undergoing neurodiagnostic procedures
It is very uncertain whether chloral hydrate oral (75 mg/kg) changes proportion of children who had sedation failure after 2 doses of… compared with pentobarbital intravenous (5 mg/kg) (very low certainty).
1 finding from 1 review
Time to adequate sedation (minutes or as measured by specific validated scales such as the Ramsay Sedation Score) · children undergoing neurodiagnostic procedures
1 finding from 1 review
Proportion of children with inadequate level of sedation (Ramsay score below 4) · children undergoing neurodiagnostic procedures
Chloral hydrate oral (100 mg/kg or 75 mg/kg) probably leads to lower proportion of children with inadequate level of sedation (Ramsay… compared with midazolam (intranasal 0.2 mg/kg or oral 0.5 mg/kg) (moderate certainty).
1 finding from 1 review
Proportion of children who had sedation failure after 1 dose of sedative agent · children undergoing neurodiagnostic procedures
Chloral hydrate oral (100 mg/kg or 75 mg/kg) showed no clear difference in proportion of children who had sedation failure after 1 dose of… compared with midazolam (intranasal 0.2 mg/kg or oral 0.5 mg/kg) (low certainty).
1 finding from 1 review
Sedation duration (minutes) · children undergoing neurodiagnostic procedures
1 finding from 1 review
Time to adequate sedation (minutes or as measured by specific validated scales such as the Ramsay Sedation Score) · children undergoing neurodiagnostic procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of children who had sedation failure or inadequate level of sedation · children undergoing neurodiagnostic procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time to adequate sedation (minutes or as measured by specific validated scales such as the Ramsay Sedation Score) · children undergoing neurodiagnostic procedures
1 finding from 1 review
Time to adequate sedation (minutes or as measured by specific validated scales such as the Ramsay Sedation Score) · children undergoing neurodiagnostic procedures
1 finding from 1 review
Proportion of children who had sedation failure or inadequate level of sedation · children undergoing neurodiagnostic procedures
Chloral hydrate oral (50 mg/kg + 50 mg/kg) showed no clear difference in proportion of children who had sedation failure or inadequate level… compared with hydroxyzine hydrochloride oral (1 mg/kg + 1 mg/kg) (low certainty).
1 finding from 1 review
Sedation duration (minutes) · children undergoing neurodiagnostic procedures
1 finding from 1 review
Time to adequate sedation (minutes or as measured by specific validated scales such as the Ramsay Sedation Score) · children undergoing neurodiagnostic procedures
1 finding from 1 review
Proportion of children with inadequate level of sedation (Ramsay score below 4) · children undergoing neurodiagnostic procedures
Chloral hydrate oral (70 mg/kg) may leads to lower proportion of children with inadequate level of sedation (Ramsay… compared with promethazine oral (1 mg/kg) (low certainty).
1 finding from 1 review
Proportion of children who had sedation failure or inadequate level of sedation · children undergoing neurodiagnostic procedures
Chloral hydrate oral (70 mg/kg) probably leads to lower proportion of children who had sedation failure or inadequate level… compared with promethazine oral (1 mg/kg) (moderate certainty).
1 finding from 1 review
Proportion of children who had sedation failure or inadequate level of sedation · children undergoing neurodiagnostic procedures
Chloral hydrate oral (50 mg/kg or 100 mg/kg) showed no clear difference in proportion of children who had sedation failure or inadequate level… compared with dexmedetomidine oral (2 µg/kg or 3 µg/kg) (moderate certainty).
1 finding from 1 review
Time to adequate sedation (minutes or as measured by specific validated scales such as the Ramsay Sedation Score) · children undergoing neurodiagnostic procedures
1 finding from 1 review