The review found no eligible studies for this question.
It is very uncertain whether benzoyl peroxide changes total number of participants with any adverse events (medium‐term… compared with salicylic acid (very low certainty).
It is very uncertain whether azathioprine or 6‐mercaptopurine changes radiologic relapse compared with 5‐aminosalicylic acid (very low certainty).
It is very uncertain whether azathioprine or 6‐mercaptopurine changes surgical relapse compared with 5‐aminosalicylic acid (very low certainty).
Azathioprine or 6‐mercaptopurine showed no clear difference in adverse events compared with 5‐aminosalicylic acid (low certainty).
It is very uncertain whether azathioprine or 6‐mercaptopurine changes serious adverse events compared with 5‐aminosalicylic acid (very low certainty).
Azathioprine or 6‐mercaptopurine may leads to higher withdrawal due to adverse events compared with 5‐aminosalicylic acid (low certainty).
Azathioprine or 6‐mercaptopurine showed no clear difference in clinical relapse compared with 5‐aminosalicylic acid (low certainty).
It is very uncertain whether azathioprine or 6‐mercaptopurine changes endoscopic relapse compared with 5‐aminosalicylic acid (very low certainty).
It is very uncertain whether methotrexate changes proportion of patients achieved clinical remission compared with 5‐aminosalicylic acid (5‐ASA) (very low certainty).
Oral 5‐ASA leads to lower failure to induce complete global or clinical remission compared with placebo (high certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
Oral 5‐ASA probably leads to lower adverse events compared with SASP (moderate certainty).
Oral 5‐ASA showed no clear difference in serious adverse events compared with SASP (low certainty).
Oral 5‐ASA probably leads to lower withdrawal due to adverse events compared with SASP (moderate certainty).
Once daily dosing showed no clear difference in failure to induce global or clinical remission compared with conventional dosing (high certainty).
Once daily dosing showed no clear difference in failure to induce global or clinical improvement compared with conventional dosing (moderate certainty).
Once daily dosing showed no clear difference in failure to induce endoscopic remission compared with conventional dosing (high certainty).