Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,788 questions · 1,849 findings · 336 reviews

No studies found 245 · 13.3%GRADE not reported 126 · 6.8%Very low 612 · 33.1%Low 512 · 27.7%Moderate 305 · 16.5%High 49 · 2.7%

Short‐acting inhaled beta‐2 agonists vs placebo

Participant‐reported symptom score: cough, wheeze and exercise tolerance · adults and children with cystic fibrosis

It is very uncertain whether short‐acting inhaled beta‐2 agonists changes participant‐reported symptom score: cough, wheeze and exercise… compared with placebo (very low certainty).

1 finding from 1 review

Antibiotics (short duration) vs prolonged‐course antibiotic therapy be used

All‐cause mortality · hospital‐acquired pneumonia

Should short‐course antibiotic therapy showed no clear difference in mortality compared with prolonged‐course antibiotic therapy be used (moderate certainty).

1 finding from 1 review

Antibiotics (short duration) vs prolonged‐course antibiotic therapy be used

Mortality NF‐GNB · hospital‐acquired pneumonia

Should short‐course antibiotic therapy showed no clear difference in mortality NF‐GNB compared with prolonged‐course antibiotic therapy be used (low certainty).

1 finding from 1 review

Antibiotics (short duration) vs prolonged‐course antibiotic therapy be used

Mortality MRSA · hospital‐acquired pneumonia

Should short‐course antibiotic therapy showed no clear difference in mortality MRSA compared with prolonged‐course antibiotic therapy be used (moderate certainty).

1 finding from 1 review

Antibiotics (short duration) vs prolonged‐course antibiotic therapy be used

Recurrence of pneumonia · hospital‐acquired pneumonia

Should short‐course antibiotic therapy showed no clear difference in recurrence of pneumonia Clinical and/or microbiological criteria compared with prolonged‐course antibiotic therapy be used (low certainty).

1 finding from 1 review

Antibiotics (short duration) vs prolonged‐course antibiotic therapy be used

Recurrence of pneumonia ‐ NF‐GNB · hospital‐acquired pneumonia

Should short‐course antibiotic therapy probably leads to higher recurrence of pneumonia NF‐GNB Clinical and/or microbiological… compared with prolonged‐course antibiotic therapy be used (moderate certainty).

1 finding from 1 review

Antibiotics (short duration) vs prolonged‐course antibiotic therapy be used

Recurrence of pneumonia ‐ MRSA · hospital‐acquired pneumonia

Should short‐course antibiotic therapy showed no clear difference in recurrence of pneumonia MRSA Clinical and/or microbiological criteria compared with prolonged‐course antibiotic therapy be used (moderate certainty).

1 finding from 1 review