Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

328 questions · 341 findings · 37 reviews · Gut

No studies found 55 · 16.1%GRADE not reported 4 · 1.2%Very low 137 · 40.2%Low 71 · 20.8%Moderate 56 · 16.4%High 18 · 5.3%

Summary of findings table (sensitivity analysis): interventions esophageal and GE‐junction carcinoma vs gastric carcinoma

Sensitivity analysis, meta‐regression analysis, second part · palliative participants with esophageal and GE‐junction carcinoma or gastric carcinoma

Summary of findings table (sensitivity analysis): interventions… probably leads to lower sensitivity analysis, meta‐regression analysis, second part compared with gastric carcinoma (moderate certainty).

1 finding from 1 review

Electromagnetic‐guided vs endoscopic‐guided postpyloric placement of nasoenteral feeding tubes

Technical success in insertion

Electromagnetic‐guided showed no clear difference in technical success in insertion compared with endoscopic‐guided postpyloric placement of nasoenteral feeding tubes (low certainty).

1 finding from 1 review

Electromagnetic‐guided vs endoscopic‐guided postpyloric placement of nasoenteral feeding tubes

Aspiration pneumonitis

Electromagnetic‐guided showed no clear difference in aspiration pneumonitis compared with endoscopic‐guided postpyloric placement of nasoenteral feeding tubes (low certainty).

1 finding from 1 review

Electromagnetic‐guided vs endoscopic‐guided postpyloric placement of nasoenteral feeding tubes

Adverse events

Electromagnetic‐guided showed no clear difference in adverse events compared with endoscopic‐guided postpyloric placement of nasoenteral feeding tubes (moderate certainty).

1 finding from 1 review

Laparoscopic pyloromyotomy vs open pyloromyotomy

Postoperative wound infection or abscess formation · infants (< 1 year of age) with hypertrophic pyloric stenosis

It is very uncertain whether laparoscopic pyloromyotomy changes postoperative wound infection or abscess formation compared with open pyloromyotomy (very low certainty).

1 finding from 1 review

Roux‐en‐Y vs Billroth‐I after distal gastrectomy

Anastomotic leakage · people undergoing distal gastrectomy for gastric cancer

It is very uncertain whether roux‐en‐Y changes incidence of anastomotic leakage compared with billroth‐I after distal gastrectomy (very low certainty).

1 finding from 1 review

Higher threshold (500 mL per six hours or greater) vs lower threshold (less than 500 mL per six hours) at time of aspiration

Mortality (at the end of · adults receiving EN via nasogastric or gastrostomy tube

It is very uncertain whether higher threshold (500 mL per six hours or greater) changes mortality (at the end of compared with lower threshold (less than 500 mL per six hours) at time of aspiration (very low certainty).

1 finding from 1 review

Higher threshold (500 mL per six hours or greater) vs lower threshold (less than 500 mL per six hours) at time of aspiration

Pneumonia · adults receiving EN via nasogastric or gastrostomy tube

It is very uncertain whether higher threshold (500 mL per six hours or greater) changes pneumonia (until discontinued or up to 28 days) compared with lower threshold (less than 500 mL per six hours) at time of aspiration (very low certainty).

1 finding from 1 review