Treatment success as defined by the authors · children (4 to 18 years) with functional abdominal pain disorders
Probiotic may leads to higher treatment success (at study end, as reported by study authors) compared with placebo (low certainty).
1 finding from 1 review
Severity of pain (at study end, using the Faces Pain Scale) · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether synbiotic changes severity of pain (at study end, using the Faces Pain Scale) compared with placebo (very low certainty).
1 finding from 1 review
Pain frequency or change in pain frequency · children (4 to 18 years) with functional abdominal pain disorders
1 finding from 1 review
Withdrawals due to adverse events · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether synbiotic changes withdrawals due to adverse events compared with placebo (very low certainty).
1 finding from 1 review
Serious adverse events · children (4 to 18 years) with functional abdominal pain disorders
1 finding from 1 review
Adverse events (any) · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether synbiotic changes adverse events (any) compared with placebo (very low certainty).
1 finding from 1 review
Pain resolution · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes complete resolution of pain (at study end, as reported by study… compared with placebo (very low certainty).
1 finding from 1 review
Severity of pain (at study end, using the Faces Pain Scale) · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes severity of pain (at study end, using the Faces Pain Scale) compared with placebo (very low certainty).
1 finding from 1 review
Pain frequency or change in pain frequency · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes frequency of pain (at study end, episodes per week) compared with placebo (very low certainty).
1 finding from 1 review
Withdrawals due to adverse events · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes withdrawals due to adverse events compared with placebo (very low certainty).
1 finding from 1 review
Serious adverse events · children (4 to 18 years) with functional abdominal pain disorders
1 finding from 1 review
Adverse events (any) · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes adverse events (any) compared with placebo (very low certainty).
1 finding from 1 review
Treatment success as defined by the authors · children (4 to 18 years) with functional abdominal pain disorders
Synbiotic may leads to higher treatment success (at study end, as reported by study authors) compared with placebo (low certainty).
1 finding from 1 review
Pain resolution · children (4 to 18 years) with functional abdominal pain disorders
Synbiotic showed no clear difference in complete resolution of pain (at study end, as reported by study… compared with placebo (low certainty).
1 finding from 1 review
Frequency of defecation (mean number of bowel movements per week) · children with chronic constipation without a physical explanation
1 finding from 1 review
Frequency of defecation (mean number of bowel movements per week) · children with chronic constipation without a physical explanation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Global improvement or treatment success, as defined by primary study · children with chronic constipation without a physical explanation
Synbiotics may leads to higher global improvement or treatment success, as defined by primary study compared with placebo (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · children with chronic constipation without a physical explanation
1 finding from 1 review
Serious adverse events · children with chronic constipation without a physical explanation
1 finding from 1 review
Frequency of defecation (mean number of bowel movements per week) · children with chronic constipation without a physical explanation
1 finding from 1 review