Pregabalin 600 mg vs placebo
Somnolence · adults with moderate or severe pain associated with painful diabetic neuropathy
1 finding from 1 review
- no estimate extracted7 studies · 1501 participantsModerate
Findings
What do systematic reviews say?
127 questions · 132 findings · 13 reviews
No studies found 13 · 9.8%GRADE not reported 4 · 3%Very low 31 · 23.5%Low 33 · 25%Moderate 27 · 20.5%High 24 · 18.2%
Pregabalin 600 mg vs placebo
Dizziness · adults with moderate or severe pain associated with painful diabetic neuropathy
1 finding from 1 review
- no estimate extracted8 studies · 1885 participantsModerate
Pregabalin 600 mg vs placebo
Withdrawals due to adverse events · adults with moderate or severe pain associated with painful diabetic neuropathy
1 finding from 1 review
- no estimate extracted8 studies · 1669 participantsHigh
Pregabalin 300 mg vs placebo
Patient Global Impression of Change much or very much improved · adults with moderate or severe pain associated with postherpetic neuralgia
1 finding from 1 review
- no estimate extracted3 studies · 568 participantsLow
Pregabalin 300 mg vs placebo
Lack of efficacy withdrawal · adults with moderate or severe pain associated with postherpetic neuralgia
1 finding from 1 review
- no estimate extracted5 studies · 933 participantsHigh
Pregabalin 300 mg vs placebo
Somnolence · adults with moderate or severe pain associated with postherpetic neuralgia
1 finding from 1 review
- no estimate extracted5 studies · 933 participantsModerate
Pregabalin 300 mg vs placebo
Dizziness · adults with moderate or severe pain associated with postherpetic neuralgia
1 finding from 1 review
- no estimate extracted5 studies · 933 participantsModerate
Pregabalin 300 mg vs placebo
Withdrawals due to adverse events · adults with moderate or severe pain associated with postherpetic neuralgia
1 finding from 1 review
- no estimate extracted5 studies · 933 participantsHigh
Pregabalin 600 mg vs placebo
Participant‐reported pain relief of 30% or greater · adults with moderate or severe pain associated with postherpetic neuralgia
1 finding from 1 review
- no estimate extracted3 studies · 537 participantsModerate
Pregabalin 600 mg vs placebo
Participant‐reported pain relief of 50% or greater · adults with moderate or severe pain associated with postherpetic neuralgia
1 finding from 1 review
- no estimate extracted4 studies · 732 participantsModerate
Pregabalin 300 mg or 600 mg vs placebo
Risk for at least one adverse event per patient · adults with moderate or severe neuropathic pain
1 finding from 1 review
- no estimate extracted15 studies · 3697 participantsHigh
Pregabalin 300 mg or 600 mg vs placebo
Serious AE · adults with moderate or severe neuropathic pain
1 finding from 1 review
- no estimate extracted17 studies · 4112 participantsHigh
Pregabalin or Gabapentin vs control or placebo medications
Acute postoperative pain 0 to 6 hours (Score 0 to 10, VAS or NRS Scale) · adults undergoing brain surgery
1 finding from 1 review
- Pharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery 2019 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 202 participantsLow
Pregabalin or Gabapentin vs control or placebo medications
Acute postoperative pain at 12 hours (Score 0 to 10, VAS or NRS Scale) · adults undergoing brain surgery
1 finding from 1 review
- Pharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery 2019 · Cochrane Headline outcomes onlyno estimate extracted1 study · 100 participantsVery low
Pregabalin or Gabapentin vs control or placebo medications
Acute postoperative pain at 24 hours (Score 0 to 10, VAS or NRS Scale) · adults undergoing brain surgery
1 finding from 1 review
- Pharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery 2019 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 202 participantsLow
Pregabalin or Gabapentin vs control or placebo medications
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults undergoing brain surgery
1 finding from 1 review
- Pharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery 2019 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 202 participantsLow
Pregabalin or Gabapentin vs control or placebo medications
Additional analgesia required (escape analgesia) · adults undergoing brain surgery
1 finding from 1 review
- Pharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery 2019 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 234 participantsLow
Pregabalin or Gabapentin vs control or placebo medications
Analgesic Success · adults undergoing brain surgery
The review found no eligible studies for this question.
1 finding from 1 review
- Pharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery 2019 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Pregabalin or Gabapentin vs control or placebo medications
Adverse effects: 1. Sedation · adults undergoing brain surgery
The review found no eligible studies for this question.
1 finding from 1 review
- Pharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery 2019 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Pregabalin or Gabapentin vs control or placebo medications
Chronic Headache · adults undergoing brain surgery
1 finding from 1 review
- Pharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery 2019 · Cochrane Headline outcomes onlyno estimate extracted54 participantsVery low