evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

897 questions · 966 findings · 73 reviews

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 269 · 27.8%GRADE not reported 101 · 10.5%Very low 284 · 29.4%Low 180 · 18.6%Moderate 107 · 11.1%High 25 · 2.6%

Any systemic treatment vs placebo

Infliximab · people with chronic plaque psoriasis

Any systemic treatment probably leads to higher infliximab compared with placebo (moderate certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Tildrakizumab · people with chronic plaque psoriasis

Any systemic treatment leads to higher tildrakizumab compared with placebo (high certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Oral Tyrosine kinase 2 (TYK2) inhibitor · people with chronic plaque psoriasis

Any systemic treatment may leads to higher oral tyrosine kinase 2 (TYK2) inhibitor compared with placebo (low certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Certolizumab · people with chronic plaque psoriasis

Any systemic treatment probably leads to higher certolizumab compared with placebo (moderate certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Ciclosporin · people with chronic plaque psoriasis

It is very uncertain whether any systemic treatment changes ciclosporin compared with placebo (very low certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Etanercept · people with chronic plaque psoriasis

Any systemic treatment probably leads to higher etanercept compared with placebo (moderate certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Methotrexate · people with chronic plaque psoriasis

Any systemic treatment may leads to higher methotrexate compared with placebo (low certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Tofacitinib · people with chronic plaque psoriasis

Any systemic treatment may leads to higher tofacitinib compared with placebo (low certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Apremilast · people with chronic plaque psoriasis

Any systemic treatment probably leads to higher apremilast compared with placebo (moderate certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Acitretin · people with chronic plaque psoriasis

It is very uncertain whether any systemic treatment changes acitretin compared with placebo (very low certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Ixekizumab · people with chronic plaque psoriasis

Any systemic treatment probably leads to higher ixekizumab compared with placebo (moderate certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Bimekizumab · people with chronic plaque psoriasis

Any systemic treatment showed no clear difference in bimekizumab compared with placebo (low certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Risankizumab · people with chronic plaque psoriasis

Any systemic treatment probably leads to lower risankizumab compared with placebo (moderate certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Ustekinumab · people with chronic plaque psoriasis

Any systemic treatment showed no clear difference in ustekinumab compared with placebo (moderate certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Guselkumab · people with chronic plaque psoriasis

Any systemic treatment showed no clear difference in guselkumab compared with placebo (moderate certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Adalimumab · people with chronic plaque psoriasis

Any systemic treatment showed no clear difference in adalimumab compared with placebo (moderate certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Brodalumab · people with chronic plaque psoriasis

Any systemic treatment showed no clear difference in brodalumab compared with placebo (moderate certainty).

2 findings from 1 review

Any systemic treatment vs placebo

Secukinumab · people with chronic plaque psoriasis

Any systemic treatment showed no clear difference in secukinumab compared with placebo (moderate certainty).

2 findings from 1 review