Death or bronchopulmonary dysplasia at 36 weeks PMA · preventing bronchopulmonary dysplasia in preterm infants
Early systemic postnatal corticosteroids leads to lower mortality or BPD at 36 weeks' PMA compared with placebo or no treatment (high certainty).
1 finding from 1 review
Gastrointestinal perforation during primary hospitalisation · preventing bronchopulmonary dysplasia in preterm infants
Early systemic postnatal corticosteroids leads to higher gastrointestinal perforation during primary hospitalisation compared with placebo or no treatment (high certainty).
1 finding from 1 review
Cerebral palsy · preventing bronchopulmonary dysplasia in preterm infants
Early systemic postnatal corticosteroids leads to higher cerebral palsy at latest reported age compared with placebo or no treatment (high certainty).
1 finding from 1 review
Death or cerebral palsy · preventing bronchopulmonary dysplasia in preterm infants
Early systemic postnatal corticosteroids showed no clear difference in mortality or cerebral palsy at latest reported age compared with placebo or no treatment (high certainty).
1 finding from 1 review
Intervention not reported
Threshold · asymptomatic newborns at the time of pulse oximetry screening
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
95% (less than or less than or equal to) · asymptomatic newborns at the time of pulse oximetry screening
1 finding from 1 review
PaO2 in mmHg (absolute values) After 24‐25 hours · pulmonary hypertension in neonates
1 finding from 1 review
Change in oxygenation index ‐ After 24 hours of treatment · pulmonary hypertension in neonates
1 finding from 1 review
All‐cause mortality · pulmonary hypertension in neonates
Sildenafil may leads to lower all‐cause mortality compared with placebo (low certainty).
1 finding from 1 review
All‐cause mortality · pulmonary hypertension in neonates
It is very uncertain whether sildenafil changes all‐cause mortality compared with active control (very low certainty).
1 finding from 1 review
All‐cause mortality · pulmonary hypertension in neonates
Sildenafil plus iNO showed no clear difference in all‐cause mortality compared with placebo plus iNO (low certainty).
1 finding from 1 review
Length of hospital stay · pulmonary hypertension in neonates
1 finding from 1 review
Overall mortality · preterm infants with severe pulmonary dysfunction
Rescue high‐frequency jet ventilation showed no clear difference in overall mortality compared with conventional ventilation (low certainty).
1 finding from 1 review
Mortality before cross‐over · preterm infants with severe pulmonary dysfunction
Rescue high‐frequency jet ventilation probably leads to lower mortality before cross‐over compared with conventional ventilation (moderate certainty).
1 finding from 1 review
Chronic lung disease · preterm infants with severe pulmonary dysfunction
Rescue high‐frequency jet ventilation showed no clear difference in chronic lung disease at 28 days of birth (CLD 28 days) compared with conventional ventilation (low certainty).
2 findings from 1 review
Severe intraventricular haemorrhage · preterm infants with severe pulmonary dysfunction
Rescue high‐frequency jet ventilation showed no clear difference in severe intraventricular haemorrhage (grades 3 and 4) compared with conventional ventilation (low certainty).
1 finding from 1 review
Neurodevelopmental outcomes · preterm infants with severe pulmonary dysfunction
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Respiratory failure · )
Nasal intermittent positive pressure ventilation (NIPPV) probably leads to lower respiratory failure compared with nasal continuous positive airway pressure (NCPAP) (by population) (moderate certainty).
1 finding from 1 review
Need for endotracheal tube ventilation · )
Nasal intermittent positive pressure ventilation (NIPPV) probably leads to lower need for endotracheal tube ventilation compared with nasal continuous positive airway pressure (NCPAP) (by population) (moderate certainty).
1 finding from 1 review
Death during study period · )
Nasal intermittent positive pressure ventilation (NIPPV) showed no clear difference in mortality during study period compared with nasal continuous positive airway pressure (NCPAP) (by population) (low certainty).
1 finding from 1 review