Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

159 questions · 167 findings · 16 reviews

No studies found 28 · 16.8%GRADE not reported 2 · 1.2%Very low 38 · 22.8%Low 53 · 31.7%Moderate 27 · 16.2%High 19 · 11.4%

Omega‐3 (with risperidone and previous ASM) vs risperidone and previous ASM only

50% or greater reduction in seizure frequency · people with ADHD and epilepsy

Omega‐3 (with risperidone and previous ASM) showed no clear difference in proportion of people achieving 50% or greater reduction in monthly… compared with risperidone and previous ASM only (low certainty).

1 finding from 1 review

Omega‐3 (with risperidone and previous ASM) vs risperidone and previous ASM only

Adverse drug events · people with ADHD and epilepsy

Omega‐3 (with risperidone and previous ASM) showed no clear difference in proportion of people experiencing adverse drug events compared with risperidone and previous ASM only (low certainty).

1 finding from 1 review

Omega‐3 (with risperidone and previous ASM) vs risperidone and previous ASM only

Proportion of individuals withdrawing from treatment · people with ADHD and epilepsy

Omega‐3 (with risperidone and previous ASM) showed no clear difference in proportion of individuals withdrawing from treatment compared with risperidone and previous ASM only (low certainty).

1 finding from 1 review

1000 mg/day omega‐3 fatty acid from flaxseed oil supplement vs placebo

Ulcer healing · people with diabetes and foot ulcers

It is very uncertain whether 1000 mg/day omega‐3 fatty acid from flaxseed oil supplement changes ulcer healing (absolute change in individual parameters of ulcer… compared with placebo (very low certainty).

4 findings from 1 review
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