Attachment change · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)
EMP + CAF showed no clear difference in clinical attachment level change compared with CAF (low certainty).
2 findings from 1 review
Occurrence of adverse effects or postoperative complications · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)
1 finding from 1 review
Sites with complete root coverage · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)
ADMG + CAF showed no clear difference in sites with complete root coverage compared with SCTG + CAF (low certainty).
1 finding from 1 review
Keratinized tissue change · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)
It is very uncertain whether EMP + CAF changes keratinized tissue change compared with SCTG + CAF (very low certainty).
1 finding from 1 review
Keratinized tissue width change · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)
GTR rm associated with bone substitutes + CAF led to lower keratinized tissue width change compared with SCTG + CAF; GRADE not reported.
1 finding from 1 review
MD -2.38 [-2.84, -1.92]
2 studies
GRADE not reported
Patients' preference for a specific procedure · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)
1 finding from 1 review
Aesthetic condition change related to patient's opinion · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)
The review found no eligible studies for this question.
1 finding from 1 review
Aesthetic condition change related to patient's opinion · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)
1 finding from 1 review
Occurrence of adverse effects or postoperative complications · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)
1 finding from 1 review
Aesthetic condition change related to patient's opinion · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)
The review found no eligible studies for this question.
1 finding from 1 review
Sites with complete root coverage · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)
GTR rm + CAF showed no clear difference in sites with complete root coverage compared with SCTG + CAF (low certainty).
1 finding from 1 review
Attachment change · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)
XCM + CAF showed no clear difference in clinical attachment level change compared with CAF (low certainty).
1 finding from 1 review
Occurrence of adverse effects or postoperative complications · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)
1 finding from 1 review
Keratinized tissue change · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)
It is very uncertain whether GTR rm + CAF changes keratinized tissue change compared with SCTG + CAF (very low certainty).
1 finding from 1 review
Change in gingival recession (REC) · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)
It is very uncertain whether EMP + CAF changes gingival recession change compared with SCTG + CAF (very low certainty).
1 finding from 1 review
Prostate cancer · Adults (general population)
Meta-analysis of observational studies (higher vs lower 25(OH)D) for Prostate cancer: OR 1.04 (95% CI 0.98 to 1.09), not statistically significant. Umbrella review outcome-level evidence grade: Substantial effect unlikely.
1 finding from 1 review
Alzheimer’s disease · Participants in observational studies
The meta-analysis of observational studies reported a SMD (to OR) of 0.08 (95% CI 0.01 to 0.63) for higher versus lower circulating vitamin D concentration.
1 finding from 1 review
Aggressive prostate cancer · Participants in observational studies
The meta-analysis of observational studies reported a OR of 0.88 (95% CI 0.68 to 1.15) for higher versus lower circulating vitamin D concentration.
1 finding from 1 review
Fasting blood glucose (mg/dL) · Adults with diabetes
Meta-analysis of randomised trials of vitamin D supplementation for Fasting glucose (Diabetes patients with normal glucose tolerance): WMD 0.01 (95% CI -0.21 to 0.23), not statistically significant. Umbrella review outcome-level evidence grade: Substantial effect unlikely.
2 findings from 1 review
WMD 0.01 [-0.21, 0.23]
Studies not reported
GRADE not reported
WMD -0.3 [-0.9, 0.3]
Studies not reported
GRADE not reported
Type 2 diabetes mellitus · Adults (general population)
Meta-analysis of observational studies (higher vs lower 25(OH)D) for Type 2 diabetes: OR 0.63 (95% CI 0.56 to 0.69), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
1 finding from 1 review