Overall postoperative morbidity · women with uterine fibroids
GnRHa treatment showed no clear difference in postoperative morbidity compared with no pretreatment or placebo before myomectomy (operative and… (low certainty).
3 findings from 1 review
Fibroid volume (cm³) · women with uterine fibroids
1 finding from 1 review
Uterine volume (cm³) · women with uterine fibroids
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Fibroid volume (cm³) · women with uterine fibroids
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Haemoglobin (g/dL) · women with uterine fibroids
1 finding from 1 review
Preoperative bleeding: (PBAC < 75) ulipristal acetate 5 mg · women with uterine fibroids
SPRM may leads to higher preoperative bleeding: (PBAC < 75) ulipristal acetate 5 mg compared with placebo (low certainty).
1 finding from 1 review
Preoperative bleeding: Reduction in bleeding to PBAC < 75 ulipristal acetate 10 mg · women with uterine fibroids
SPRM may leads to higher preoperative bleeding: Reduction in menstrual bleeding (PBAC < 75)… compared with placebo (low certainty).
1 finding from 1 review
Preoperative bleeding: Change in menstrual blood loss from baseline to end of treatment · women with uterine fibroids
1 finding from 1 review
Haemoglobin (g/dL) · women with uterine fibroids
1 finding from 1 review
Adverse events · women with uterine fibroids
SPRM showed no clear difference in adverse events compared with placebo (low certainty).
1 finding from 1 review
Preoperative bleeding · women with uterine fibroids
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · women with uterine fibroids
GnRHa treatment probably leads to higher adverse events compared with placebo or no pretreatment (preoperative outcomes) (moderate certainty).
1 finding from 1 review
Control of bleeding (cure or improvement to acceptable level) At 2 years · women with heavy menstrual bleeding
Surgery probably leads to higher control of bleeding (cure or improvement to acceptable level) At 4… compared with oral medication (moderate certainty).
3 findings from 1 review
RR 2.66 [1.94, 3.64]
1 study · 186 participants
Moderate
RR 1.29 [1.06, 1.57]
1 study · 173 participants
Low
RR 1.14 [0.97, 1.34]
1 study · 140 participants
Very low
Satisfaction rate: surgery versus LNG‐IUS Endometrial ablation versus LNG‐IUS At 2 years · women with heavy menstrual bleeding
Surgery showed no clear difference in satisfaction rate: surgery versus LNG‐IUS Endometrial ablation… compared with LNG‐IUS (low certainty).
1 finding from 1 review
Proportion of women with adverse events Endometrial ablation versus LNG‐IUS. At one year · women with heavy menstrual bleeding
Surgery probably leads to lower proportion of women with adverse events Endometrial ablation versus… compared with LNG‐IUS (moderate certainty).
1 finding from 1 review
Overall satisfaction with treatment At 2 years · women with heavy menstrual bleeding
Surgery probably leads to higher overall satisfaction with treatment At 2 years compared with oral medication (moderate certainty).
1 finding from 1 review
Overall satisfaction with treatment At 5 years · women with heavy menstrual bleeding
It is very uncertain whether surgery changes overall satisfaction with treatment At 5 years compared with oral medication (very low certainty).
1 finding from 1 review
Adverse events at 4 months · women with heavy menstrual bleeding
Surgery probably leads to lower adverse events at 4 months compared with oral medication (moderate certainty).
1 finding from 1 review
Objective control of bleeding: menstrual loss under 80 ml per cycle LNG‐IUS versus hysterectomy At 1 year · women with heavy menstrual bleeding
Surgery probably leads to higher objective control of bleeding: menstrual loss under 80 ml per cycle… compared with LNG‐IUS (moderate certainty).
1 finding from 1 review
Subjective control of bleeding: PBAC no more than 75 per cycle Endometrial resection or ablation versus LNG‐IUS At 1 year · women with heavy menstrual bleeding
Surgery may leads to higher subjective control of bleeding: PBAC no more than 75 per cycle… compared with LNG‐IUS (low certainty).
1 finding from 1 review