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Evidence found and GRADE certainty

83 questions · 109 findings · 12 reviews · Oral and maxillofacial surgery

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No studies found 2 · 1.8%GRADE not reported 95 · 87.2%Very low 2 · 1.8%Low 10 · 9.2%Moderate 0 · 0%High 0 · 0%

Cleft lip and/or palate (CL/P) vs No cleft lip and/or palate (non-CL/P)

Restorative index (RI = f/[d+f]) in the primary dentition · Children in the primary dentition with non-syndromic cleft lip and/or palate (CL/P) and comparable children without CL/P

The restorative index tended to be lower in children with CL/P (3 of 5 studies), indicating a lower proportion of restoratively managed carious teeth; not pooled (narrative; ungraded).

1 finding from 1 review
  • Caries in children with and without orofacial clefting: A systematic review and meta-analysis. 2022 All outcomes
    Children with CL/P and comparable non-CL/P children across 12 countries (India, Brazil, China, Sweden, UK, USA, Germany, Greece, Ireland, Netherlands, Jordan, Thailand); studies published 1989-2021
    Of the five studies for which the RI could be calculated, three of them (Dahllof 1989; Nagappan 2019; Veiga 2016) showed a lower RI for children with CL/P compared to children with no CL/P demonstrating a lower…
    5 studies
    GRADE not reported