Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

141 questions · 144 findings · 9 reviews · HIV/AIDS

No studies found 1 · 0.7%GRADE not reported 5 · 3.5%Very low 27 · 18.8%Low 48 · 33.3%Moderate 54 · 37.5%High 9 · 6.3%

An extended antiretroviral regimen administered to mothers for 28 weeks vs an extended NVP regimen administered to infants

Infants with Severe Adverse Events · HIV‐infected mothers and their breastfeeding infants

An extended antiretroviral regimen administered to mothers for 28… showed no clear difference in infants with Severe Adverse Events compared with an extended NVP regimen administered to infants (low certainty).

1 finding from 1 review

An extended antiretroviral regimen administered to mothers for 28 weeks vs an extended NVP regimen administered to infants

Mothers with Severe Adverse Events · HIV‐infected mothers and their breastfeeding infants

An extended antiretroviral regimen administered to mothers for 28… may leads to higher mothers with Severe Adverse Events compared with an extended NVP regimen administered to infants (low certainty).

1 finding from 1 review

An extended NVP regimen administered to infants for 14 weeks vs sdNVP plus ZDV (1 week)

Infants with Probably Related Severe Adverse Events · Breastfeeding infants of HIV‐infected mothers

It is very uncertain whether an extended NVP regimen administered to infants for 14 weeks changes infants with Probably Related Severe Adverse Events11 compared with sdNVP plus ZDV (1week) (very low certainty).

1 finding from 1 review

An extended NVP plus ZDV dual regimen administered to infants for 14 weeks vs sdNVP plus ZDV (1 week)

HIV Transmission at 9 months among those whose HIV diagnostic testing was negative within 48 hours of birth · Breastfeeding infants of HIV‐infected mothers

An extended NVP plus ZDV regimen administered to infants for 14 weeks probably leads to lower HIV Transmission at 9 months among those whose HIV diagnostic… compared with sdNVP plus ZDV (1 week) (moderate certainty).

1 finding from 1 review

Social cognitive theory for promotion of condom use vs no intervention

Consistent application of condom by FSWs · sex workers

Social cognitive theory for promotion of condom use showed no clear difference in consistent application of condom by FSWs compared with no intervention (moderate certainty).

2 findings from 1 review

Social cognitive theory for promotion of condom use vs no intervention

HIV knowledge among FSWs at 6‐month · sex workers

It is very uncertain whether social cognitive theory for promotion of condom use changes HIV knowledge among FSWs at 6‐month compared with no intervention (very low certainty).

1 finding from 1 review

Social cognitive theory for promotion of condom use vs no intervention

Psychosocial barriers to condom use among FSWs at 6‐month · sex workers

Social cognitive theory for promotion of condom use showed no clear difference in psychosocial barriers to condom use among FSWs at 6‐month compared with no intervention (moderate certainty).

1 finding from 1 review

Social cognitive theory for promotion of condom use vs no intervention

Psychosocial barriers to condom use self‐efficacy among FSWs at 6‐month · sex workers

It is very uncertain whether social cognitive theory for promotion of condom use changes psychosocial barriers to condom use self‐efficacy among FSWs at… compared with no intervention (very low certainty).

1 finding from 1 review

Promotion of female and male condom vs promotion of male condom

HIV incidence among FSWs at 3‐month · sex workers

Promotion of female and male condom showed no clear difference in HIV incidence among FSWs at 3‐month compared with promotion of male condom (low certainty).

1 finding from 1 review

Promotion of female and male condom vs promotion of male condom

Chlamydia incidence among FSWs at 3‐month · sex workers

Promotion of female and male condom leads to lower chlamydia incidence among FSWs at 3‐month compared with promotion of male condom (high certainty).

1 finding from 1 review