Cochrane · systematic review · CD004536

Nutritional interventions for reducing morbidity and mortality in people with HIV

Grobler, L, Siegfried, N, Visser, ME, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library

HIV/AIDSAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 4 · 57.1%Moderate 2 · 28.6%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Balanced nutritional supplement compared to counselling or nutritional placebo in patients with weight loss for reducing morbidity and mortality in people with HIV

Population: patients with reducing morbidity and mortality in people with HIV
7 questions
OutcomeEffectEvidenceStatus / GRADE
Energy intake (kcal/day)
Balanced nutritional supplement vs counselling or nutritional placebo
no estimate extracted3 studies · 131 participantsLow
Downgraded: risk of bias, imprecision
Protein intake (g/day)
Balanced nutritional supplement vs counselling or nutritional placebo
no estimate extracted2 studies · 81 participantsLow
Downgraded: risk of bias, imprecision
Body weight
Balanced nutritional supplement vs counselling or nutritional placebo
no estimate extracted4 studies · 233 participantsModerate
Downgraded: risk of bias, imprecision
Fat mass measured in % of TBW
Balanced nutritional supplement vs counselling or nutritional placebo
no estimate extracted4 studies · 233 participantsModerate
Downgraded: risk of bias, imprecision
Fat free mass
Balanced nutritional supplement vs counselling or nutritional placebo
no estimate extracted3 studies · 218 participantsLow
Downgraded: risk of bias, imprecision
CD4
Balanced nutritional supplement vs counselling or nutritional placebo
no estimate extracted2 studies · 81 participantsLow
Downgraded: risk of bias, imprecision
Viral load (log10 copies/ml)
Balanced nutritional supplement vs counselling or nutritional placebo
no estimate extracted1 study · 66 participantsVery low
Downgraded: risk of bias, imprecision