Findings

What do systematic reviews say?

82 questions · 82 findings · 4 reviews

No studies found 12 · 14.6%GRADE not reported 0 · 0%Very low 25 · 30.5%Low 29 · 35.4%Moderate 16 · 19.5%High 0 · 0%

Diarrhoea · patients with induction therapy in lupus nephritis

Mycophenolate mofetil (MMF) probably leads to higher diarrhoea compared with IV cyclophosphamide (CPA) (moderate certainty).

1 finding from 1 review

Immunosuppressive treatment for proliferative lupus nephritis 2018 · Cochrane Headline outcomes only
RR 2.42 [1.64, 3.58]
4 studies · 609 participants
Moderate

Complete renal remission · Patients with proliferative lupus nephritis

Mycophenolate mofetil (MMF) + tacrolimus (TAC) may leads to higher complete renal remission compared with IV cyclophosphamide (CPA) (low certainty).

1 finding from 1 review

Immunosuppressive treatment for proliferative lupus nephritis 2018 · Cochrane Headline outcomes only
RR 2.38 [1.07, 5.3]
2 studies · 402 participants
Low