Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

294 questions · 295 findings · 16 reviews · Schizophrenia

No studies found 79 · 26.8%GRADE not reported 32 · 10.8%Very low 99 · 33.6%Low 55 · 18.6%Moderate 17 · 5.8%High 13 · 4.4%

HALOPERIDOL vs OLANZAPINE

Specific behaviour ‐ threat or injury to self or others average change score (ABS, high = worse) at 2 hours · psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes specific behaviour ‐ threat or injury to self or others compared with OTHER ANTIPSYCHOTIC: e. OLANZAPINE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OLANZAPINE

Global outcome ‐ need for benzodiazepine during 24 hours · psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes global outcome ‐ need for benzodiazepine during 24 hours compared with OTHER ANTIPSYCHOTIC: e. OLANZAPINE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OLANZAPINE

Adverse effects: Specific ‐ dystonia during 24 hours · psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes adverse effects: Specific ‐ dystonia during 24 hours compared with OTHER ANTIPSYCHOTIC: e. OLANZAPINE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OTHER ANTIPSYCHOTIC: f. PERPHENAZINE

Global outcome: general ‐ no improvement · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes global outcome: general ‐ no improvement compared with OTHER ANTIPSYCHOTIC: f. PERPHENAZINE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OTHER ANTIPSYCHOTIC: f. PERPHENAZINE

Adverse effect: Specific ‐ hypotensive episode · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes adverse effect: Specific ‐ hypotensive episode compared with OTHER ANTIPSYCHOTIC: f. PERPHENAZINE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OTHER ANTIPSYCHOTIC: f. PERPHENAZINE

Adverse effect ‐ discontinued due to EPS · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes adverse effect ‐ discontinued due to EPS compared with OTHER ANTIPSYCHOTIC: f. PERPHENAZINE (very low certainty).

1 finding from 1 review