What do systematic reviews say?

Autogenic drainage vs intrapulmonary percussive ventilation (400 bpm)

The review found no eligible studies for this question.

• Autogenic drainage for airway clearance in cystic fibrosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Autogenic drainage vs intrapulmonary percussive ventilation (400 bpm)

The review found no eligible studies for this question.

• Autogenic drainage for airway clearance in cystic fibrosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Autogenic drainage vs intrapulmonary percussive ventilation (400 bpm)

The review found no eligible studies for this question.

• Autogenic drainage for airway clearance in cystic fibrosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Autogenic drainage vs intrapulmonary percussive ventilation (400 bpm)

The review found no eligible studies for this question.

• Autogenic drainage for airway clearance in cystic fibrosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Autogenic drainage vs conventional physiotherapy

• Autogenic drainage for airway clearance in cystic fibrosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 36 participants
  Very low

Autogenic drainage vs spontaneous cough

• Autogenic drainage for airway clearance in cystic fibrosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 14 participants
  Very low

Autogenic drainage vs spontaneous cough

The review found no eligible studies for this question.

• Autogenic drainage for airway clearance in cystic fibrosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Needle aspiration (needle removed immediately after aspiration) vs intercostal tube drainage

It is very uncertain whether needle aspiration (needle removed immediately after aspiration) changes need for intercostal tube drainage compared with intercostal tube drainage (very low certainty).

• Needle aspiration versus intercostal tube drainage for pneumothorax in the newborn 2019 · Cochrane Headline outcomes only
  RR 0.7 [0.56, 0.88]
  1 study · 70 participants
  Very low

Needle aspiration (needle or angiocatheter left in situ) vs intercostal tube drainage

It is very uncertain whether needle aspiration (needle or angiocatheter left in situ) changes need for intercostal tube drainage compared with intercostal tube drainage (very low certainty).

• Needle aspiration versus intercostal tube drainage for pneumothorax in the newborn 2019 · Cochrane Headline outcomes only
  RR 0.01 [0, 0.21]
  1 study · 72 participants
  Very low

Pre‐operative biliary drainage vs direct surgery

It is very uncertain whether pre‐operative biliary drainage changes mortality compared with direct surgery (very low certainty).

• Pre‐operative biliary drainage for obstructive jaundice 2012 · Cochrane Headline outcomes only
  RR 1.12 [0.73, 1.71]
  6 studies · 520 participants
  Very low

Pre‐operative biliary drainage vs direct surgery

It is very uncertain whether pre‐operative biliary drainage changes morbidity ICH‐GCP classification compared with direct surgery (very low certainty).

• Pre‐operative biliary drainage for obstructive jaundice 2012 · Cochrane Headline outcomes only
  Rate ratio 1.66 [1.28, 2.16]
  6 studies · 503 participants
  Very low

Intervention not reported

• Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 101 participants
  Low

Intervention not reported

• Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 738 participants
  Low

Intervention not reported

• Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 160 participants
  Low

Intervention not reported

• Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 587 participants
  Low

Intervention not reported

• Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 343 participants
  Moderate

Intervention not reported

• Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 405 participants
  Moderate

Isoxsuprine vs placebo

It is very uncertain whether isoxsuprine changes complete leg ulcer closure (defined as 100% epithelization or skin… compared with placebo (very low certainty).

• Interventions for treating leg ulcers in people with sickle cell disease 2021 · Cochrane Headline outcomes only
  RR 1.2 [0.4, 3.62]
  1 study · 40 participants
  Very low

Propionyl‐L‐carnitine vs placebo

The review found no eligible studies for this question.

• Interventions for treating leg ulcers in people with sickle cell disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Arginine butyrate plus standard care alone vs usual care

It is very uncertain whether arginine butyrate plus standard care alone changes complete leg ulcer closure (defined as 100% epithelization or skin… compared with standard care alone (very low certainty).

• Interventions for treating leg ulcers in people with sickle cell disease 2021 · Cochrane Headline outcomes only
  RR 3.72 [0.9, 15.35]
  1 study · 23 participants
  Very low