Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

382 questions · 384 findings · 98 reviews

No studies found 54 · 14.1%GRADE not reported 37 · 9.6%Very low 116 · 30.2%Low 99 · 25.8%Moderate 60 · 15.6%High 18 · 4.7%

Magnesium aspartate vs placebo

Benzodiazepine discontinuation, end of intervention · adults who withdraw from chronic benzodiazepine use

It is very uncertain whether magnesium aspartate changes benzodiazepine discontinuation, end of intervention compared with placebo (very low certainty).

1 finding from 1 review

Homéogène 46/Sedatif PC (homeopathic drugs) vs placebo

Benzodiazepine discontinuation, end of intervention · adults who withdraw from chronic benzodiazepine use

It is very uncertain whether homéogène 46/Sedatif PC (homeopathic drugs) changes benzodiazepine discontinuation, end of intervention compared with placebo (very low certainty).

1 finding from 1 review

Carbamazepine vs tricyclic antidepressants (TCAs)

Benzodiazepine discontinuation, end of intervention · adults who withdraw from chronic benzodiazepine use

Carbamazepine showed no clear difference in benzodiazepine discontinuation, end of intervention compared with tricyclic antidepressant (low certainty).

1 finding from 1 review