Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

522 questions · 532 findings · 23 reviews

No studies found 88 · 16.5%GRADE not reported 174 · 32.7%Very low 111 · 20.9%Low 92 · 17.3%Moderate 46 · 8.6%High 21 · 3.9%

Intervention not reported

Combination of patient reminder or recall with provider reminder intervention · children, adolescents, and adults with a need for routine immunizations, excluding travel immunizations

The intervention probably leads to higher combination of patient reminder or recall with provider reminder… (moderate certainty).

1 finding from 1 review

Intervention not reported

Knowledge or understanding (Different measures used by the studies: knowledge of vaccine‐preventable diseases, vaccines, contraindications to vaccination, or a combination, on varying scales) Final time point (3 or 6 months post‐intervention) · parents of preschool‐aged children or expectant parents
1 finding from 1 review

Intervention not reported

Attitudes or beliefs (Different measures used by the studies: perceived severity of vaccine‐preventable diseases, perceived necessity of vaccines, or a combination, on varying scales) Final time point (3 or 6 months post‐intervention) · parents of preschool‐aged children or expectant parents
1 finding from 1 review

Antihypertensive drug class vs placebo

Beta‐blocker/thiazide combination (any dose) Mean duration of 10 weeks · children (from 1 to 18 years of age) with hypertension from primary or secondary causes
2 findings from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Treatment time · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Cost-benefit consideration · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Patient discomfort · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Stability of the correction · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Quality of life · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Adverse effects including pain, gingivitis, enamel decalcification and root resorption · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Aesthetics · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Assessment of the alignment of the lower front teeth using any method or index · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Total studies: 282 RCTs Total participants: 50,812 Number of treatments: 65 Geometry of the network** · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…
1 finding from 1 review