Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

589 questions · 615 findings · 63 reviews · Headline outcomes only

No studies found 116 · 18.9%GRADE not reported 59 · 9.6%Very low 206 · 33.5%Low 156 · 25.4%Moderate 78 · 12.7%High 0 · 0%

CBT vs ALL OTHER PSYCHOLOGICAL THERAPIES

Satisfaction with treatment: leaving the study early Endpoint data (events) · patients with schizophrenia

CBT may leads to lower satisfaction with treatment ‐ leaving the study early for any reason compared with ALL OTHER PSYCHOLOGICAL THERAPIES (low certainty).

1 finding from 1 review

CBT vs WAIT LIST

Remission of anxiety diagnoses (ITT analysis) i.e. no longer meeting criteria for DSM or ICD anxiety diagnosis at the end of the trial. · children and adolescents with anxiety disorders

CBT probably leads to higher remission of anxiety diagnoses (ITT analysis) i.e. no longer meeting… compared with wait‐list (moderate certainty).

1 finding from 1 review

CBT vs active control

Remission of anxiety diagnoses (ITT analysis) i.e. no longer meeting criteria for DSM or ICD anxiety diagnosis at the end of the trial. · children and adolescents with anxiety disorders

CBT showed no clear difference in remission of anxiety diagnoses (ITT) analysis i.e. no longer meeting… compared with active controls (moderate certainty).

1 finding from 1 review

CBT vs treatment

Remission of anxiety diagnoses (ITT analysis) i.e. no longer meeting criteria for DSM or ICD anxiety diagnosis at the end of the trial. · children and adolescents with anxiety disorders

CBT showed no clear difference in remission of anxiety diagnoses (ITT analysis) i.e. no longer meeting… compared with treatment (moderate certainty).

1 finding from 1 review

CBT vs TAU

AEs · chronic pain (excluding headache) in adults
3 findings from 2 reviews · compare the 2 reviews

CBT vs TAU

Reduction in pain intensity · chronic pain (excluding headache) in adults

It is very uncertain whether CBT changes pain intensity (number of people with ≥ 30 % improvement)… compared with TAU (at follow‐up) (very low certainty).

2 findings from 2 reviews · compare the 2 reviews