Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

107 questions · 124 findings · 13 reviews · Oral Health

No studies found 3 · 2.4%GRADE not reported 68 · 54.8%Very low 43 · 34.7%Low 3 · 2.4%Moderate 7 · 5.6%High 0 · 0%

Partial caries removal (single stage; residual dentinal caries sealed into the tooth definitively) vs Complete caries removal

Signs or symptoms of pulpal disease · Patients with carious teeth, affecting any tooth surface(s), in unrestored primary and permanent teeth

Partial caries removal (single stage; residual dentinal caries… showed no clear difference in signs or symptoms of pulpal disease compared with complete caries removal (low certainty).

1 finding from 1 review

No dentinal caries removal (caries sealed under a preformed metal crown or restoration without removing dentinal caries) vs Complete caries removal

Restoration failure · Patients with carious teeth, affecting any tooth surface(s), in unrestored primary and permanent teeth

No dentinal caries removal (caries sealed under a preformed metal… probably leads to lower failure of restorations compared with complete caries removal (moderate certainty).

1 finding from 1 review

No dentinal caries removal (caries sealed under a preformed metal crown or restoration without removing dentinal caries) vs Complete caries removal

Signs or symptoms of pulpal disease · Patients with carious teeth, affecting any tooth surface(s), in unrestored primary and permanent teeth

No dentinal caries removal (caries sealed under a preformed metal… showed no clear difference in signs or symptoms of pulpal disease compared with complete caries removal (moderate certainty).

1 finding from 1 review

Calcium hydroxide (CH) vs Biodentine

Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing DPC or pulpotomy

Biodentine appeared to perform better than calcium hydroxide for success, but the evidence was not pooled (2 RCTs; ungraded).

1 finding from 1 review

Colour clinical examination (visual shade categorization: yellow, light brown, dark brown, black) vs Hardness clinical examination (tactile texture categorization: soft, medium/leathery, hard)

Discriminant power for caries severity: effect size (f) for microbial load (log10 CFU) between lesion categories · Patients with dentine carious lesions (deciduous/permanent teeth; children and adults)

The weighted effect size favoured hardness (f=2.62) over colour (f=0.46) for discriminating microbial load, supporting hardness as the more reliable examination (ungraded).

1 finding from 1 review

Colour clinical examination (visual shade categorization: yellow, light brown, dark brown, black) vs Hardness clinical examination (tactile texture categorization: soft, medium/leathery, hard)

Discriminant power for caries severity: mean difference in log10 CFU (microbial load) between lesion categories · Patients with dentine carious lesions (deciduous/permanent teeth; children and adults)

For yellow-vs-other colour compared with soft-vs-harder hardness, hardness was significantly the more discriminant test (pooled WMD -3.87, 95% CI -4.46 to -2.87; ungraded).

6 findings from 1 review
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Atraumatic restorative treatment with GIC vs Conventional restoration

Restoration failure · Children (3-13 years) with dentine caries in primary teeth, no pulpal involvement

ART with GIC was reported to increase the odds of restoration failure versus conventional restoration (OR 1.60; ungraded).

1 finding from 1 review

Atraumatic restorative treatment with GIC vs Conventional treatment

Pain during the procedure (primary analysis) · Children (3-13 years) with dentine caries in primary teeth, no pulpal involvement

The reported estimate for procedural pain with ART versus conventional treatment was inconclusive (ungraded).

1 finding from 1 review

Composite resin with etch-and-rinse (total-etch) adhesion vs Composite resin with self-etch adhesion (same universal adhesive)

Treatment failure (annual failure rate) · Children with moderately deep dentine caries in primary molars, no pulp therapy

Etch-and-rinse adhesion failed more than self-etch (19.5% vs 7.0% annual failure) in one RCT; low quality of evidence (ungraded).

1 finding from 1 review

Selective caries removal (SCR) + composite resin vs Complete caries removal (CCR) + composite resin

Treatment failure (annual failure rate) · Children with deep dentine caries in primary molars restored with composite resin (indirect pulp treatment; pulpotomy only if pulp exposed…

Complete caries removal with composite resin had an annual failure rate of 6.8% in primary molars (single high-risk-of-bias RCT; low quality of evidence; not GRADE-rated).

2 findings from 1 review

Hall technique vs Compomer restoration or non-restorative caries treatment

Treatment failure (annual failure rate) · Children (aged 3-8 years) with 2-surface occluso-proximal dentine caries in primary molars, no pulp therapy

Preformed metal (Hall) crowns had a low reported annual failure rate (3.1%) versus compomer (14.7%) in one RCT; low quality of evidence (ungraded).

1 finding from 1 review

High-viscosity GIC atraumatic restorative treatment vs No control

Restoration survival · Children with decayed primary molar teeth

Multi-surface ART restorations had a reported survival rate of 73% at 1 year.

4 findings from 1 review
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Single-surface ART restoration using high-viscosity glass ionomer vs Multi-surface ART with high-viscosity GIC

Restoration failure · Children (2-9 years) with caries in posterior primary teeth

Single-surface ART restorations had a low reported mean annual failure rate (about 5%; ungraded).

1 finding from 1 review

High-viscosity GIC atraumatic restorative treatment vs Conventional restoration

Restoration survival · Children with occlusoproximal caries in primary teeth

Multiple reviews reported similar restoration survival for ART versus conventional restorations in occlusoproximal cavities (ungraded).

1 finding from 1 review