Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

96 questions · 190 findings · 27 reviews

No studies found 5 · 2.6%GRADE not reported 176 · 92.6%Very low 8 · 4.2%Low 1 · 0.5%Moderate 0 · 0%High 0 · 0%

Cessation of water fluoridation (fluoride removed from the water supply) vs Continued fluoridated water

Change in proportion of caries-free children (deciduous or permanent teeth) · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience)

The review found no eligible studies for this question.

1 finding from 1 review

Cessation of water fluoridation (fluoride removed from the water supply) vs Continued fluoridated water

Early childhood caries experience (mean dmft) · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience)

The review found no eligible studies for this question.

1 finding from 1 review
  • No evidence to determine the effect of the cessation of water fluoridation on caries in deciduous teeth. No included study reported change in dmft following cessation.
    0 studies
    No studies found

Cessation of water fluoridation (fluoride removed from the water supply) vs Continued fluoridated water

Dental caries in permanent teeth · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience)
1 finding from 1 review
  • Water fluoridation for the prevention of dental caries 2015 · Cochrane All outcomes
    Follow-up 3 years
    Insufficient evidence to determine the effect of the cessation of water fluoridation on caries. One study (Maupome 2001), at high risk of bias, over 3 years found no increase in caries in the fluoride-ended group…
    1 study · 9249 participants
    Very low

Cessation of water fluoridation (fluoride removed from the water supply) vs Continued fluoridated water

Disparities in caries across socioeconomic status (SES) · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience)

The review found no eligible studies for this question.

1 finding from 1 review

Women who experienced preterm birth vs Women who did not experience preterm birth (term)

Decayed, missing, filled surfaces (DMFS) · pregnant women

Women who experienced preterm birth did not have a significantly different DMFS than those who did not (mean difference -0.15, 95% CI -3.40 to 3.09; 3 studies; I2=89%); certainty of evidence not graded.

1 finding from 1 review
  • Dental caries and preterm birth: a systematic review and meta-analysis. 2018 All outcomes
    Pregnant women assessed around delivery in observational studies across multiple countries (Mexico, Malawi, India, France, Jordan, Finland, Tanzania); mostly retrospective cohort and case-control designs
    MD -0.15 [-3.40, 3.09]
    3 studies · 2594 participants
    GRADE not reported

Women who experienced preterm birth vs Women who did not experience preterm birth (term)

Dental caries · pregnant women

Women who experienced preterm birth did not have significantly higher DMFT than those who did not (mean difference 1.56, 95% CI -0.28 to 3.41; 5 studies; I2=92%); certainty of evidence not graded.

1 finding from 1 review
  • Dental caries and preterm birth: a systematic review and meta-analysis. 2018 All outcomes
    Pregnant women assessed around delivery in observational studies across multiple countries (Mexico, Malawi, India, France, Jordan, Finland, Tanzania); mostly retrospective cohort and case-control designs
    MD 1.56 [-0.28, 3.41]
    5 studies · 2963 participants
    GRADE not reported

High-viscosity glass-ionomer ART restorations vs Conventional treatment using H-GIC (rotary instruments)

Discomfort associated with the procedure · People with dental caries in primary teeth (mainly children)

ART using high-viscosity glass ionomer cement (H-GIC), hand… showed no clear difference in participant experience (discomfort during procedure) compared with conventional treatment using H-GIC (rotary instruments); GRADE not reported.

1 finding from 1 review

ART using composite resin vs Conventional treatment using composite resin

Participant experience (dental anxiety) · Children with carious primary teeth

ART using composite resin showed no clear difference in participant experience (dental anxiety) compared with conventional treatment using composite resin; GRADE not reported.

1 finding from 1 review

ART using glass ionomer cement (GIC) vs Amalgam restoration

Participant experience (co-operation during procedure) · Children and adolescents with dental caries (primary teeth and permanent immature teeth)
1 finding from 1 review

Cessation of water fluoridation (fluoride removed from the water supply) vs Continued fluoridated water

Adverse effects · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience)

The review found no eligible studies for this question.

1 finding from 1 review

Learning disability (CLD) vs No learning disability (CNLD)

Care index (CI), permanent teeth · Children aged 1-18 years

The care index (met dental care need) for permanent teeth could not be meta-analyzed because no study reported variance; it was lower or equal in children with learning disabilities in 5 of 8 studies (certainty not graded).

1 finding from 1 review

Learning disability (CLD) vs No learning disability (CNLD)

Restorative index (RI), permanent teeth · Children aged 1-18 years

The restorative index for permanent teeth could not be meta-analyzed (no variance data); it was lower or equal in children with learning disabilities in 4 of 9 studies, and the pattern suggested more extraction- than restoration-based care in CLD (certainty not graded).

1 finding from 1 review

Learning disability (CLD) vs No learning disability (CNLD)

Unmet dental treatment need · Children aged 1-18 years

Narrative reports from 6 studies suggested greater unmet dental treatment need in children with learning disabilities (5 of 6 studies), but no quantitative data were available (certainty not graded).

1 finding from 1 review