What do systematic reviews say?

Tacrolimus 0.1% vs pimecrolimus 1%

Tacrolimus 0.1% probably leads to higher physician's assessment of global response of improvement, clear or… compared with pimecrolimus 1% (moderate certainty).

• Topical tacrolimus for atopic dermatitis 2015 · Cochrane Headline outcomes only
  RR 1.8 [1.34, 2.42]
  2 studies · 506 participants
  Moderate

Infliximab vs placebo

Infliximab probably leads to higher physician global assessment compared with placebo (moderate certainty).

• Interventions for hidradenitis suppurativa 2015 · Cochrane Headline outcomes only
  RR 4.8 [1.66, 13.9]
  1 study · 33 participants
  Moderate

Oral tetracycline vs topical clindamycin

• Interventions for hidradenitis suppurativa 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 34 participants
  Low

Oral tetracycline vs topical clindamycin

• Interventions for hidradenitis suppurativa 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 34 participants
  Low

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyloestradiol and norgestrel

• Interventions for hidradenitis suppurativa 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 17 participants
  Moderate

Intense pulsed light vs no treatment

Intense pulsed light may leads to higher participant global assessment: satisfaction with treatment… compared with no treatment (low certainty).

• Interventions for hidradenitis suppurativa 2015 · Cochrane Headline outcomes only
  RR 9.67 [2.01, 46.43]
  1 study · 34 participants
  Low

Intense pulsed light vs no treatment

Intense pulsed light may leads to higher participant global assessment: satisfaction with treatment ‐ axilla… compared with no treatment (low certainty).

• Interventions for hidradenitis suppurativa 2015 · Cochrane Headline outcomes only
  RR 21 [1.37, 322.28]
  1 study · 24 participants
  Low

Intense pulsed light vs no treatment

Intense pulsed light showed no clear difference in participant global assessment: satisfaction with treatment ‐ groin… compared with no treatment (low certainty).

• Interventions for hidradenitis suppurativa 2015 · Cochrane Headline outcomes only
  RR 5 [0.31, 79.94]
  1 study · 8 participants
  Low

Intense pulsed light vs no treatment

Intense pulsed light showed no clear difference in participant global assessment: satisfaction with treatment ‐… compared with no treatment (low certainty).

• Interventions for hidradenitis suppurativa 2015 · Cochrane Headline outcomes only
  RR 3 [0.24, 37.67]
  1 study · 2 participants
  Low

Staphage lysate vs placebo broth

Staphage lysate probably leads to higher physician global assessment compared with placebo broth (moderate certainty).

• Interventions for hidradenitis suppurativa 2015 · Cochrane Headline outcomes only
  RR 6.25 [1.68, 23.27]
  1 study · 27 participants
  Moderate

Flutamide 250 mg b.i.d. vs placebo

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 60 participants
  Very low

Flutamide 250 mg once to b.i.d. vs spironolactone 100 mg

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 40 participants
  Very low

Spironolactone 100 mg vs placebo

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Low

Finasteride 5 mg to 7.5 mg vs placebo

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 62 participants
  Very low

Metformin 500 mg to 2550 mg per day vs placebo

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 264 participants
  Low

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyl estradiol 30 μg + desogestrel 0.15 mg

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 164 participants
  Low

Finasteride 5 mg vs spironolactone 100 mg

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 34 participants
  Low

Flutamide 250 mg once to b.i.d. vs metformin 1275 mg to 1700 mg per day

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 95 participants
  Very low

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 226 participants
  Very low

Cetirizine 10 to 20 mg vs placebo

Cetirizine 10 to 20 mg may leads to higher complete suppression of urticaria Global assessment of symptom scores compared with placebo (low certainty).

• H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only
  RR 2.72 [1.51, 4.91]
  2 studies · 178 participants
  Low