Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

406 questions · 416 findings · 20 reviews · Common Mental Disorders

No studies found 73 · 17.5%GRADE not reported 9 · 2.2%Very low 144 · 34.6%Low 123 · 29.6%Moderate 59 · 14.2%High 8 · 1.9%

Tricyclic antidepressants vs placebo

Adverse events (at 4, 6 or 12 weeks) · adults with insomnia

Tricyclic antidepressants showed no clear difference in adverse events (at 4, 6 or 12 weeks) compared with placebo (low certainty).

1 finding from 1 review