Findings

What do systematic reviews say?

84 questions · 94 findings · 9 reviews

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No studies found 7 · 7.4%GRADE not reported 14 · 14.9%Very low 5 · 5.3%Low 47 · 50%Moderate 21 · 22.3%High 0 · 0%

Intervention not reported

Cancer Number of participants diagnosed with cancer · heart transplant recipients

The intervention showed no clear difference in cancer Number of participants diagnosed with cancer (low certainty).

1 finding from 1 review

Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
RR 1.01 [0.45, 2.28]
4 studies · 576 participants
Low

Interleukin‐2 RA vs no induction

Mortality Mortality at latest · heart transplant recipients

Interleukin‐2 RA showed no clear difference in mortality Mortality at latest compared with no induction (low certainty).

1 finding from 1 review

Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
RR 1.53 [0.85, 2.76]
4 studies · 576 participants
Low

Interleukin‐2 RA vs no induction

Acute rejection Acute rejection grade 3A or more verified by biopsy · heart transplant recipients

Interleukin‐2 RA showed no clear difference in acute rejection Acute rejection grade 3A or more verified by biopsy compared with no induction (low certainty).

1 finding from 1 review

Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
RR 0.73 [0.46, 1.17]
4 studies · 576 participants
Low

Interleukin‐2 RA vs no induction

Infection Number of participants diagnosed with infection · heart transplant recipients

Interleukin‐2 RA showed no clear difference in infection Number of participants diagnosed with infection compared with no induction (low certainty).

1 finding from 1 review

Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
RR 0.99 [0.79, 1.24]
3 studies · 545 participants
Low